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Liotrix

Latest prescription information about Liotrix. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Liotrix
Pronunciation : LYE-oh-triks
Therapeutic Classification : Thyroid and Antithyroid Agents
ICD Code : Y42.1
Trade Name(s): 
International- Thyrolar 1.
Why it is prescribed (Indications) : This medication is a thyroid hormone, prescribed for hypothyroidism. It works by supplying the thyroid hormones normally produced by the body.
When it is not to be taken (Contraindications): Contraindicated in patients with uncorrected adrenal cortical insufficiency, untreated thyrotoxicosis, and hypersensitivity.

Pregnancy Category :

A B C D X
Category A : Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).

Dosage & When it is to be taken : For children: The recommended dose range is 3.1 mcg to 18.75 mcg of T 3 and 6.25 mcg to 75 mcg T 4 daily.
Adult- The recommended dose is 1 tablet (6.25 mcg T 3 /25 mcg T 4) for every 2 to 3 weeks.
How it should be taken : It comes as a tablet to take by mouth, once a day before breakfast.
Warnings and Precautions : 
* Caution should be exercised in patients with history of sugar, osteoporosis, hardening or narrowing of the blood vessels, high blood pressure, high blood cholesterol, chest pain, abnormal heart rhythm, heart attack, malabsorption, underactive adrenal gland, kidney or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* Patient may experience with few symptoms like trembling or shaking of hands, nervousness, difficulty in sleeping, headache, change in appetite, diarrhea, weight loss, increased sweating; if it is so adjust the dosage accordingly.
* Monitor thyroid function, blood sugar level regularly while taking this medication.
Side Effects : 
Central Nervous System - Fatigue, sluggishness, increase in weight, weakness, headache, depression, anxiety, tremor, and sleeplessness.
Skin - Hair loss, itching, rash, dry skin, hives and excessive sweating.
Heart - Palpitations, high blood pressure, fast heart rate and irregular heart beat.
Musculoskeletal - Joint/Muscle pain.
Gastrointestinal - Nausea and vomiting.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it in refrigerator (2 to 8°C). Do not freeze it.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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