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Lidocaine and Prilocaine

Latest prescription information about Lidocaine and Prilocaine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Lidocaine and Prilocaine
Pronunciation : LYE-doe-kane-PRIL-oh-kane
Therapeutic Classification : Local Anesthetics
ICD Code : Y48.3
Trade Name(s): 
India- Lovelong, Primla, Asthesia, Prilox, Satisfaction gel.
International- Emla.
Why it is prescribed (Indications) : This medication is a dermal anesthesia, prescribed for tingling, pricking or numbness of a person's skin. It works by blocking nerve signals in the body.
When it is not to be taken (Contraindications): Hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : Topical- The recommended dose range is 1gm to 20gms over 10 to 200 cm2 of skin surface for 1 to 4 hours.
How it should be taken : It comes as a cream, to be applied on intact skin and covered with an occlusive dressing.
Warnings and Precautions : 
* Do not apply on broken/irritated skin or open wounds.
* Caution should be exercised in patients with history of certain blood disorder (G6PD-genetic disorder, especially in children), heart disease, kidney disease, liver disease, elderly, children, during pregnancy and breastfeeding.
* Avoid getting this medication into eyes, nose, or mouth.
* Avoid excess dosage.
Side Effects : 
Most Common- Local- redness, burning sensation and swelling.
Others- Itching, rash and paleness.
Other Precautions : 
* For external use only.
Storage Conditions : 
Store it at controlled room temperature (15-30°C).

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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