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Levomethadyl Acetate

Latest prescription information about Levomethadyl Acetate. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Levomethadyl Acetate
Pronunciation : lee-voe-METH-a-dil
Therapeutic Classification : Antiarrhythmics
ICD Code : Y52.2
Trade Name(s): 
International- Orlaam.
Overview : Note: Withdrawn from the U.S. market.
Why it is prescribed (Indications) : This medication is a narcotic analgesic, prescribed for opiate addiction. 
When it is not to be taken (Contraindications): Contraindicated in patients with known or suspected QT prolongation, electrolyte imbalance, and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : Adults- The recommended dose or initial patients 20 and 40 milligrams (mg).
Maintenance: 60 to 90mg, 3 times a week.
How it should be taken : It comes as a solution to take by mouth, as directed by your physician.
Warnings and Precautions : 
* Caution should be exercised in patients with asthma, emphysema, or other chronic lung disease, head injury, Crohn's disease, enlarged prostate, gallstones, heart disease, high blood pressure, kidney or liver disease, underactive thyroid, during pregnancy and breastfeeding.
* Avoid alcohol consumption.
Side Effects : 
General - Increased tears, runny nose, sneezing, yawning, perspiration, gooseflesh, fever, chilliness alternating with flushing.
Central Nervous System - Restlessness, irritability, insomnia, weakness, anxiety, depression, tremors.
Gastrointestinal - Abdominal cramps, loss of appetite, nausea, vomiting, diarrhea, and weight loss.
Miscellaneous - Dilated pupils, fast heart rate, and body aches.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at controlled room temperature (15°-30°C).

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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