Information about Leuprolide

Generic Name : Leuprolide
Up-to-date prescription details regarding Leuprolide are provided here.

Pronunciation : loo-PROL-lide

Learn the correct pronunciation of the Leuprolide, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

Therapeutic Classification : Miscellaneous Endocrine Agents

Trade Names/Brand Names of Leuprolide

India :

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International :

Lupron Depot, Eligard, Viadur

Why is Leuprolide Prescribed? (Indications)

This medication is a gonadotropin-releasing hormone (GnRH) agonist (hormonal chemotherapy), prescribed for prostate cancer, endometriosis, uterine fibroids, and central precocious puberty. It decreases levels of certain hormones in the body.

When should Leuprolide not be taken? (Contraindications)

Contraindicated in pregnant women and patients with known hypersensitivity.

What is the dosage of Leuprolide?

SC- The recommended dose is 1 mg/day (0.2 ml or 20 unit mark) administered as a single dose.

How should Leuprolide be taken?

It comes as a solution for injection to be administered by a healthcare provider under the skin.

What are the warnings and precautions for Leuprolide?

• Caution should be exercised in patients with history of sugar, high blood sugar, urinary problems, spinal cord problems, heart disease, stroke, weak bones, osteoporosis, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may decrease certain hormone levels, they may cause severe side effects such as breast size changes, breast soreness or tenderness, testicular changes, irregular periods, decreased sexual ability, hot flashes. If it is so consult with your doctor.

• Patient may develop with increased risk of bone weakness, sugar; if you experience with unusual pain or tiredness consult with your doctor.

• Monitor blood testosterone levels, prostate-specific antigen (PSA), hemoglobin, blood glucose and bone density regularly while taking this medication.

What are the side effects of Leuprolide?

Heart - Heart failure, ECG changes, high blood pressure, murmur, inflammation of blood vessels, fluid accumulation and swelling.
Gastrointestinal - Loss of appetite, constipation, nausea and vomiting.
Genitourinary - Decreased testicular size, breast enlargement in male, breast tenderness or pain, hot flashes, impotence urine frequency/urgency, blood in urine and urinary tract infection.
Blood - Anemia.
Musculoskeletal - Bone/muscle pain.
♦ Central Nervous System - Dizziness, lightheadedness, general pain, headache, convulsions and sleep disorders.
Respiratory - Difficulty in breathing and nasal congestion.
Skin - Skin inflammation.
Miscellaneous - Weakness.