Medindia » Medication Manual » Lenalidomide

Lenalidomide

Updated on : May - 2012
Latest prescription information about Lenalidomide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email print Print Save this page Save Syndicate Syndicate
Generic Name : Lenalidomide
Pronunciation : LEN a LID o mide
Therapeutic Classification : Immunomodulators
Trade Name(s): 
India- Lenangio, Lenid, Mydolen.
International- Revlimid.
Why it is prescribed (Indications) : This medication is an immunomodulatory agent, prescribed for certain types of myelodysplastic syndrome and multiple myeloma either alone or with other medications. It works by helping the bone marrow to produce normal blood cells and by killing abnormal cells in the bone marrow.
When it is not to be taken (Contraindications): Contraindicated in pregnant and breastfeeding women, and hypersensitivity.

Pregnancy Category :

A B C D X
Category X : Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Dosage & When it is to be taken : The recommended starting dose is 25 mg once daily orally with water on days 1-21 of repeated 28-day cycles.
How it should be taken : It comes as a capsule to take by mouth, with food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of kidney disease, any allergy.
Patient may develop with increased risk of secondary malignancy. If it is so consult with your healthcare provider
Side Effects : 
Blood - Anemia, decrease in white blood cells and platelets.
General - Fatigue, fever, swelling in the extremities, chest pain and tiredness.
Gastrointestinal - Constipation, diarrhea, nausea, vomiting, abdominal pain and dry mouth.
Musculoskeletal - Muscle cramps, back pain and bone pain.
Central Nervous system - Dizziness, tremor, difficulty in swallowing and nerve disease.
Respiratory - Difficulty in breathing, inflammation of pharynx, lungs.
Infection - Upper respiratory tract infection, pneumonia, urinary tract infection and inflammation of sinus.
Skin - Rash, increased sweating, dry skin and itching.
Metabolic - Loss of appetite, decrease in calcium/potassium, dehydration and decreased weight.
Eye - Blurred vision.
Heart - High or low blood pressure.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature.
♦ Safety Labeling Changes Approved By FDA

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z