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Lansoprazole

Updated on : September - 2012
Latest prescription information about Lansoprazole. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Lansoprazole
Pronunciation : lan-SOE-pra-zole
Therapeutic Classification : Antiulcers
ICD Code : Y53.0
Trade Name(s): 
India- Acilanz Cap, Arlan Cap, Bal-Lanz Cap, Cap Loc Od Cap, Chexid Cap, Culans Cap, Domsin-La Cap, Juniorlanzol Tab, L-30 Cap, Lacy Cap, Lampo Cap, Lan Cap, Lance Cap, Lance-D Cap, Lancer Cap, Lanchek Cap, Lancibay Tab, Lancid Cap, Lancidom Cap, Lancus Enteric-Coated Cap, Lands-30 Cap, Lanip Cap, Lanip-D Cap, Lanoz Tab, Lanpro Cap, Lansec Cap, Lanset Cap, Lanso Cap, Lans-Od Cap, Lansofast Cap, Lansol Cap, Lansomac Cap, Lansoriv Cap, Lansoz Cap, Lanspep Cap, Lanspro Cap, Lanspro-D Cap, Lanzap Cap, Lanzee Cap, Lanzee-Dm Cap, Lanzip-30 Tab, Lanzo Cap, Lanzol Cap, Lanzopen Cap, Lapra-D Cap, Lasole Cap, Lasole-D Cap, Laz-30 Cap, L-Dom Cap, Leed Cap, Leedom Cap, Legend Cap, Lepez Enteric-Coated Cap, Lesozap-D Cap, Levant Cap, Lezo Cap Cap, Liza Cap, Liza-D Cap, Locid-30 Cap, Locid-D Cap, Lp-30 Cap, Lupizole Cap, Okalan Cap, Olez-30 Cap, Prompro Cap, Protogut Cap, Reflan Cap, Sanlap Soft-Gelatin Caps, Splanz Cap, Taurlans-30 Cap, Zapacid Cap, Zes-30 Cap.
International- Prevacid , Prevacid NapraPAC.
Why it is prescribed (Indications) : 
This medication is a proton pump inhibitor, prescribed for gastric ulcer, duodenal ulcer, gastroesophageal reflux disease (GERD), erosive esophagitis (inflammation of esophagus), and Zollinger-Ellison (gastric acid hyper secretion) syndrome. It blocks the enzyme in the stomach that produces acid.  
When it is not to be taken (Contraindications): 
Known hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
Adult- PO- The recommended dose is 15 – 30 mg once daily. Higher dose is needed in Zollinger – Ellison syndrome.
How it should be taken : 
It comes as a delayed-release (long-acting) capsule and granules to make a delayed-release solution (liquid) to take by mouth. It is usually taken once a day, before eating. Do not crush or chew the capsules. Swallow the medication whole. Injection administered into the vein.
Warnings and Precautions : 
*While taking sucralfate (Carafate), take it at least 30 minutes after lansoprazole.
*It may affect liver function.
*Gastric malignancy should be ruled out.
* Caution should be exercised in patients with osteoporosis, liver problem, bowel cancer, any allergy, who are taking other medications, during pregnancy and breastfeeding.
Side Effects : 
Central Nervous System- Headache.
Skin- Severe allergic reactions.
Eye and ENT- Speech disorder.
Gastrointestinal- Diarrhea, abdominal pain, constipation, nausea, inflammation of pancreas and vomiting.
Genitourinary- Urinary retention.
Blood- Decrease in white blood cells, platelets, neutrophils, anemia and bleeding.
Liver- Liver damage.
Miscellaneous- Injection site pain/reaction and life threatening allergic reactions.
Other Precautions : 
*Do not change the dose or stop taking this medication unless advised by health care provider.
Storage Conditions : 
Injection: Store at 25°C (77°F). Oral: Store at 25°C (77°F). Store it in an airtight container and keep away from children.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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