Generic Name : Ivacaftor
International- Kalydeco. Why it is prescribed (Indications) :
This medication is a CF transmembrane conductance regulator agonist, prescribed for cystic fibrosis (CF) in patients more than 6 years old. It works by improving the function of a protein in the body to decrease the build-up of thick mucus in the lungs and improving other symptoms of cystic fibrosis. When it is not to be taken (Contraindications):
It should not be co-administered with antibiotics rifampin, seizure medications and St. John’s Wort.
Dosage & When it is to be taken :
Adults and pediatric patients age 6 years and older: one 150 mg tablet taken orally every12 hours with fat-containing food. How it should be taken :
It comes as a tablet to take by mouth, with fat-containing food. Warnings and Precautions :
* Caution should be exercised in patients with history of liver or kidney problems, who are taking other medications, any allergy, during pregnancy and breastfeeding.
* Avoid drinking grapefruit juice, or eat grapefruit or Seville oranges while taking this medication.
* Always take it with fatty food.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication. Side Effects :
Most Common - Headache, upper respiratory tract infection, stomach (abdominal) pain, diarrhea, rash, nausea, and dizziness.
* Avoid excess dosage. Storage Conditions :
Store it at room temperature (20°C to 25°C).
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