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Ivacaftor
Updated on : August - 2012
Latest prescription information about Ivacaftor. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Ivacaftor
Trade Name(s): International- Kalydeco. Why it is prescribed (Indications) : This medication is a CF transmembrane conductance regulator agonist, prescribed for cystic fibrosis (CF) in patients more than 6 years old. It works by improving the function of a protein in the body to decrease the build-up of thick mucus in the lungs and improving other symptoms of cystic fibrosis. When it is not to be taken (Contraindications): It should not be co-administered with antibiotics rifampin, seizure medications and St. John’s Wort.
Dosage & When it is to be taken : Adults and pediatric patients age 6 years and older: one 150 mg tablet taken orally every12 hours with fat-containing food. How it should be taken : It comes as a tablet to take by mouth, with fat-containing food. Warnings and Precautions : * Caution should be exercised in patients with history of liver or kidney problems, who are taking other medications, any allergy, during pregnancy and breastfeeding. * Avoid drinking grapefruit juice, or eat grapefruit or Seville oranges while taking this medication. * Always take it with fatty food. * It may cause dizziness, do not drive a car or operate machinery while taking this medication. Side Effects : Most Common - Headache, upper respiratory tract infection, stomach (abdominal) pain, diarrhea, rash, nausea, and dizziness. * Avoid excess dosage. Storage Conditions : Store it at room temperature (20°C to 25°C). |
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Reference
- Food and Drug Administration (FDA)
- National Institutes of Health (NIH)
- PubMed
- CIMS
- Indian Pharma Reference Guide 2012
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