Itraconazole - Drug Information

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General Information on Itraconazole

Generic Name : Itraconazole

Pronunciation : i- tra –ko- na- zole

Latest prescription information about Itraconazole. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y40.7 | Therapeutic Classification : Antifungals

Why is Itraconazole Prescribed? (Indications)

This medication is an antifungal agent, prescribed for treating fungal infections. It interferes with the formation of the fungal cell membrane and kills fungi.

When should Itraconazole not to be taken? (Contraindications)

Contraindicated in patients with severe kidney problems, congestive heart failure, co-administration with cisapride, oral midazolam, nisoldipine, pimozide, quinidine, dofetilide, triazolam and levacetylmethadol, hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Itraconazole?

Adult- PO- The recommended dose is 100 to 200 mg once daily (2 capsules).

How should Itraconazole be taken?

It comes as a capsule to take by mouth, on an empty stomach.

What are the warnings and precautions for Itraconazole?

• Caution should be exercised in patients with history of HIV infection, weakened immune system, kidney or liver problems, abnormal liver function tests, lung or breathing problems, irregular heartbeat, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
• It may cause dizziness, do not drive a car or operate machinery while taking this medication.
• It may affect blood sugar level; monitor sugar level regularly while taking this medication.

What are the side effects of Itraconazole?

•   Gastrointestinal : Nausea, vomiting, diarrhea, abdominal pain and loss appetite.
•   Body as a Whole : Fluid retention, fatigue, fever and uneasiness.
•   Skin : Rash and itching.
•   Central Nervous System : Headache, dizziness, decreased sexual activity and drowsiness.
•   Heart : High blood pressure.
•   Metabolic : Decrease in potassium level.
•   Genitourinary : Impotence.
•   Liver : Abnormal liver function.
•  Respiratory: Difficulty in breathing.

What are the other precautions for Itraconazole?

Avoid excess dosage.

What are the storage conditions of Itraconazole?

Store it at room temperature and in an airtight container.

♦ Safety Labeling Changes Approved By FDA

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