Isoxsuprine hydrochloride - Drug InformationGeneric Name : Isoxsuprine hydrochloride | Pronunciation : eye-SOX-you-preen HIGH-droe-KLOR-ide
India- Adilin, B-Prox, Cuprox, Dulovas, Duvabel-Sr, Duvadilan, Elprox-Sr, Feprox-Sr, Fisox, Idilan, Ioril, Isarin-Sr, Iscom, Isopreg Inj, Isoriv , Isowin, Isox, Isoxsan, Myprox, Perivalan, Pregnin Re, Pridilan, Risox-Sr, Servolax, Suprex, Suprime-40, Supritom, Suprivas, Suprox, Tidilan, Tockiso, Tocolyte, Tpdilan, Trisnox, Udilan, Utocare-Sr, Utorax, Vasodilan, X-Ride.
Why it is prescribed (Indications) :
This medication is a vasodilator, prescribed for peripheral vascular disease, relief of symptoms associated with cerebrovascular insufficiency, and premature labor. It relaxes blood vessels, which makes them wider and allows blood to pass through them more easily.
When it is not to be taken (Contraindications):Contraindicated in patients with history of arterial bleeding, immediately after childbirth and labor.
Pregnancy Category :
Category C :Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Dosage & When it is to be taken :
Adult: PO- Peripheral vascular disease: The recommended dose is 10-20 mg 3-4 times/day.
IV/IM- To arrest premature labour- The recommended dose is 200-500 mcg/min via IV infusion until control is achieved, then 10 mg 3-8 hourly via IM inj for several days.
How it should be taken :
It comes as a tablet to take by mouth, with or without food.
It also comes as a solution for injection to be administered by a healthcare provider into the vein and large muscle.
Warnings and Precautions :Caution should be exercised in patients with history of bleeding problems, who are taking other medications, any allergy, during pregnancy and breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Side Effects :
Central Nervous System - Dizziness.
Heart - Low blood pressure, palpitations, fast heart rate, lung swelling and flushing.
Gastrointestinal - Nausea, vomiting and abdominal distress.
Miscellaneous - Rash and allergic reactions such as hives, difficulty breathing, tightness in the chest.