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Irbesartan

Latest prescription information about Irbesartan. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Irbesartan
Pronunciation : IR-be-SAR-tan
Therapeutic Classification : angiotensin receptor blockers
Trade Name(s): 
India- Aprovel Tab, Irbest Tab, Irbecard, Irovel Tab, Irovel-H Tab, Sebri, Xarb Tab, Xarb-H Tab.
International- Avapro.
Why it is prescribed (Indications) : 
This medication is an angiotensin II receptor blocker (ARB), prescribed for high blood pressure either alone or combined with other medications. It is also used to treat kidney disorders in patients with type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control blood sugar). This medication relaxes blood vessels and helps to lower blood pressure.

When it is not to be taken (Contraindications): 


Contraindicated in patients with hypersensitivity, pregnancy and lactation.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
Oral- Hypertension- Adult: 150 mg once daily, increased to 300 mg once daily if necessary. For patients with intravascular volume depletion: Initially, 75 mg once daily.
Child: 6-16 yr: 75 mg once daily increased to 150 mg if necessary.
Elderly: >75 yr: Initially 75 mg once daily.
Renal impairment: Haemodialysis: Initially, 75 mg once daily.
Oral- Diabetic nephropathy in Type 2 diabetes mellitus- Adult: 150 mg once daily, increased to 300 mg once daily if necessary.
How it should be taken : 
It comes as a tablet to take by mouth. It is usually taken once a day with or without food.
Special Instruction : 
*This medication may not work as well in Black patients. Discuss any questions or concerns with your doctor.
*Dehydration, excessive sweating, vomiting, or diarrhea may increase the risk of low blood pressure. Contact your healthcare provider immediately.
*Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you don't feel normal.
*Caution needed while using in children, elderly patients.
*Lab tests, including blood pressure, blood electrolyte levels and heart, kidney, or liver function, may be performed while using this medication.
Side Effects : 
Heart- Chest pain, fast heart beat and edema.
Central Nervous System- Headache, anxiety/nervousness and dizziness.
Gastrointestinal- Diarrhea, stomach upset, heartburn, abdominal pain and nausea/vomiting.
Respiratory- Upper respiratory tract infection, influenza, runny nose and sinus abnormality.
Miscellaneous- Musculoskeletal pain/trauma, fatigue, urinary tract infection and rash.
Other Precautions : 
*Avoid abrupt withdrawal.
Storage Conditions : 
Store at 25�C. Store it in an airtight container and keep away from children.

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