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Medindia » Medication Manual » Ipilimumab

Ipilimumab

Updated on : October - 2012

Latest prescription information about Ipilimumab. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Generic Name : Ipilimumab

Pronunciation : IP i LIM ue mab

Therapeutic Classification : Monoclonal antibodies

ICD Code : Y43.4

Trade Name(s):
International- Yervoy.

Why it is prescribed (Indications) : This medication is a monoclonal antibody, prescribed for melanoma (a type of skin cancer). It helps the body to slow or stop the growth of cancer cells.

When it is not to be taken (Contraindications): Hypersensitivity.

Pregnancy Category :

A B C D X

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : The recommended dose is 3 mg/kg administered intravenously over 90 minutes every 3 weeks for a total of four doses.

How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein.

Warnings and Precautions :
* Caution should be exercised in patients with history of autoimmune disease, liver impairment, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
* Monitor liver and thyroid functions regularly while taking this medication.

Side Effects :
Most Common - Fatigue, diarrhea, itching, rash and intestinal inflammation.

Other Precautions :
* Avoid excess dosage.

Storage Conditions :
Store it under refrigeration at 2°C to 8°C.