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Interferon Beta-1B

Updated on : December - 2012
Latest prescription information about Interferon Beta-1B. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Interferon Beta-1B
Pronunciation : IN-ter-FEER-on BAY-ta
Therapeutic Classification : Chemotherapy
Trade Name(s): 
International- Betaseron.
Why it is prescribed (Indications) : 
This medication is an interferon, prescribed for multiple sclerosis (MS). 
When it is not to be taken (Contraindications): Contraindicated in patients with a history of hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
SC- The recommended dose is 0.25 mg injected every other day.
How it should be taken : 
It comes as a powder for injection (diluted with fluid), to be administered by a healthcare provider under the skin.
Warnings and Precautions : 
* Caution should be exercised in patients with history of anemia, low white blood cells, blood problems, diabetes, anxiety, depression, mental illness, seizures, trouble in falling sleep, prostate, skin, thyroid, blood, heart, or liver disease; any allergy, who are taking other medication, children, during pregnancy and breastfeeding.
* Patient may develop with increased risk of suicidal thoughts; watch them carefully.
* It may reduce platelet counts; avoid injury or bruising.
* Monitor complete blood cell counts, liver function, and thyroid function regularly while taking this medication.
Side Effects : 
Most Common - Decrease in white blood cells, injection site reaction, weakness, flu-like symptom complex, headache, and pain.
Blood - Decrease in white blood cells, lymph node disease.
Central Nervous System - Headache, sleeplessness, incoordination.
Vascular Disorders - High blood pressure.
Respiratory - Difficulty in breathing.
Gastrointestinal - Abdominal pain.
Liver - Increase in liver enzymes.
Skin - Rash.
Musculoskeletal - Increased muscle tome, muscle pain.
Genitourinary - Urinary urgency, irregular periods, impotence.
General - Injection site reaction, weakness, flu-like symptoms, pain, fever, chills, swelling in the extremities, chest pain, uneasiness, injection site necrosis.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (25°C).

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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