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Generic Name : Insulin Detemir
Pronunciation : in' su lin - de' te mir
Trade Name(s):
International- Levemir Flexpen. This medication is a long-acting form of the hormone insulin, prescribed for diabetes in patients with need of insulin to control their diabetes. It is a long-acting insulin. It helps to control the levels of glucose (sugar) in the blood. It works by helping move sugar from the blood into other body tissues where it is used for energy. It also stops the liver from producing more sugar. When it is not to be taken (Contraindications):
When it is to be taken : SC- In insulin-native patients with type 2 diabetes who are not well controlled on oral antidiabetic drugs: Initial- 0.1-0.2 u/kg once daily in the evening or 10 u 1-2 times/day, adjust subsequently based on glucose control. In patients on basal insulin only: May substitute with insulin detemir on a unit-for-unit basis based on the current basal insulin dosage; adjust subsequently to achieve glucose targets. How it should be taken : It comes as a solution for injection, administered subcutaneously (under the skin) by your healthcare provider, either 1 time or 2 times a day. Special Instruction : * It may affect liver or kidney functions. * Regular monitoring of blood glucose and HbA1c. * Continuous rotation of the injection site within a given area to reduce injection site reactions (allergic reactions that result in cutaneous necrosis). * Inform your doctor about your pregnancy and lactation. Side Effects : Central Nervous System- Headache, neuropathy, seizure and sensory disturbances. Skin- Inflammation of injection site, itching, rash and skin disorder. Eye and ENT- Blurred vision and inflammation of nasopharynx. Gastrointestinal- Abdominal pain, diarrhea and nausea. Genitourinary- Urinary tract infection. Hypersensitivity- Hypersensitivity reaction (including anaphylaxis, angioedema, fast pulse, hypotension, rash, shortness of breath, sweating) and insulin antibody production. Lab-tests- Elevated alkaline phosphatase. Metabolic- Low blood sugar, low potassium level and weight gain. Respiratory- Upper respiratory tract infection. Miscellaneous- Accidental injury, chest pain, absent reflexes, influenza and swelling in the extremities. *It is not to be used in insulin infusion pumps. Storage Conditions : Subcutaneous: Unopened preparation: Store between 2-8°C (36-46°F). Do not freeze. |
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