Insulin Detemir - Drug Information

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General Information on Insulin Detemir

Generic Name : Insulin Detemir

Pronunciation : in' su lin - de' te mir

Latest prescription information about Insulin Detemir. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y42.3 | Therapeutic Classification : Antidiabetics

Trade Names/Brand Names of Insulin Detemir

India : 

International : 

Levemir Flexpen

Why is Insulin Detemir Prescribed? (Indications)

This medication is a long-acting form of the hormone insulin, prescribed for diabetes in patients with need of insulin to control their diabetes. It is a long-acting insulin. It helps to control the levels of glucose (sugar) in the blood. It works by helping move sugar from the blood into other body tissues where it is used for energy. It also stops the liver from producing more sugar. 

When should Insulin Detemir not to be taken? (Contraindications)

Do not admin by intravenous, intramuscular or via insulin infusion pump. Hypersensitivity to any component.

Pregnancy Category

A B C D X

Category B :

Animal studies have failed to demonstrate a risk to the fetus and appropriate studies on pregnant women are lacking.

What is the dosage of Insulin Detemir?

SC- In insulin-native patients with type 2 diabetes who are not well controlled on oral antidiabetic drugs: Initial- 0.1-0.2 u/kg once daily in the evening or 10 u 1-2 times/day, adjust subsequently based on glucose control. In patients on basal insulin only: May substitute with insulin detemir on a unit-for-unit basis based on the current basal insulin dosage; adjust subsequently to achieve glucose targets.

How should Insulin Detemir be taken?

It comes as a solution for injection, administered subcutaneously (under the skin) by your healthcare provider, either 1 time or 2 times a day.

What are the warnings and precautions for Insulin Detemir?

• It may affect liver or kidney functions.
• Regular monitoring of blood glucose and HbA1c.
• Continuous rotation of the injection site within a given area to reduce injection site reactions (allergic reactions that result in cutaneous necrosis).
• Inform your doctor about your pregnancy and lactation.
Patient may develop hypoglycemia. In such case dose reduction is needed.

What are the side effects of Insulin Detemir?

  Central Nervous System: Headache, neuropathy, seizure and sensory disturbances.
  Skin: Inflammation of injection site, itching, rash and skin disorder.
  Eye and ENT: Blurred vision and inflammation of nasopharynx.
  Gastrointestinal: Abdominal pain, diarrhea and nausea.
  Genitourinary: Urinary tract infection.
  Hypersensitivity: Hypersensitivity reaction (including anaphylaxis, angioedema, fast pulse, hypotension, rash, shortness of breath, sweating) and insulin antibody production.
  Lab-tests: Elevated alkaline phosphatase.
  Metabolic: Low blood sugar, low potassium level and weight gain.
  Respiratory: Upper respiratory tract infection.
  Miscellaneous: Accidental injury, chest pain, absent reflexes, influenza and swelling in the extremities.

What are the other precautions for Insulin Detemir?

It is not to be used in insulin infusion pumps.

What are the storage conditions of Insulin Detemir?

Subcutaneous: Unopened preparation: Store between 2-8°C (36-46°F). Do not freeze.

♦ Safety Labeling Changes Approved By FDA

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