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Infliximab

Latest prescription information about Infliximab. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Infliximab
Pronunciation : in flix' i mab
Therapeutic Classification : Antirheumatics
ICD Code : Y45.4
Trade Name(s): 
International- Remicade.
Why it is prescribed (Indications) : 
This medication is a monoclonal antibody, prescribed for autoimmune disorders, joint pain, Crohn's disease, inflammatory bowel disease, ankylosing spondylitis, psoriasis.  It blocks the action of TNF-alpha, a substance in the body that causes inflammation.
When it is not to be taken (Contraindications): Allergic to any components of the product, patients with moderate to severe heart failure should not receive more than 5 mg/kg.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
It is administered intravenously in a dose of 5 mg/kg on day 1, second week, sixth week, and then after every 6 weeks.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
*Avoid vaccination while taking this medication.
*Caution should be exercised in patients with history of hepatitis B.
*It may develop an active infection while using this medication.
Side Effects : 
Gastrointestinal- Stomach pain, nausea, loss of appetite and blood in stool.
Heart- Chest pain and shortness of breath.
Miscellaneous- Headache, runny nose, vaginal itching, flushing, rash, joint pain and seizures.
Other Precautions : 
*It may affect blood clots, avoid unusual bruising or bleeding.
Storage Conditions : 
Store vials (powder for injection) in refrigerator (36° to 46°F). Do not freeze.

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Member Comments ( 1 )
hi sir me Parvesh kumar and i am illness with ankylosing spondilities about 9 years. my treatment is continuing A.I.I.M.S. and no relief. so
doctor suggestion injection infliximob .
Kindly give your suggestion about my illness if i became perfectely all right yes &no
PARVESH KUMAR

(Posted by Parvesh093, India Date : 9/5/2012 )

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
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  • Indian Pharma Reference Guide 2012
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