Indinavir - Drug Information

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General Information on Indinavir

Generic Name : Indinavir

Pronunciation :  in-DIN-a-veer

Latest prescription information about Indinavir. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y41.5 | Therapeutic Classification : Antiretroviral Agents

Trade Names/Brand Names of Indinavir

Why is Indinavir Prescribed? (Indications)

This medication is a protease inhibitor, prescribed for human immunodeficiency virus (HIV) infection in adults that slow the spread of HIV infection in the body.  It works by blocking the growth of HIV.

When should Indinavir not to be taken? (Contraindications)

Contraindicated in patients with severe liver damage and hypersensitivity.
It should not be co-administered with ovastatin, or simvastatin.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Indinavir?

PO- The recommended dose is 800 mg 8 hourly orally.

How should Indinavir be taken?

It comes as a capsule to take by mouth, on an empty stomach.

What are the warnings and precautions for Indinavir?

1 hour time interval should be there in between didanosine and indinavir.
Caution should be exercised in patients with history of hemophilia or kidney or liver disease, alcohol abuse, high blood sugar, high cholesterol, kidney stones, urinary problems, elderly, children, during pregnancy and breastfeeding.
It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.
It does not stop the spread of HIV to others; avoid sexual contact, sharing of needles, or injection supplies.
It may affect blood sugar level; monitor sugar level regularly.

What are the side effects of Indinavir?

   Heart : Chest pain, blood supply disorder and heart attack.
   Central Nervous System : Headache, dizziness, fatigue, general discomfort, drowsiness, oral tingling and depression.
   Skin : Itching, rash, redness of the skin, Stevens Johnson syndrome, darkening of skin or nail, hair loss, ingrown toenails and nail infection.
   Eye and ENT : Taste perversion.
   Gastrointestinal : Abdominal pain, nausea, vomiting, acid regurgitation, loss of appetite, diarrhea, increased appetite, upset stomach and abdominal distension.
   Genitourinary : Kidney stones, absence of urine, kidney insufficiency, kidney failure, pus in urine, interstitial nephritis sometimes with indinavir crystal deposits and crystals in urine.

What are the other precautions for Indinavir?

Avoid excess dosage.

What are the storage conditions of Indinavir?

Store it at 25C.
A desiccant (drying agent) is included with your capsules; keep this in your medicine bottle at all times.

♦ Safety Labeling Changes Approved By FDA

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