Generic Name : Idursulfase Pronunciation : EYE dur SUL fase Therapeutic Classification : Enzyme Replacement Therapy
International- Elaprase. Why it is prescribed (Indications) :
This medication is a lysosomal enzyme, prescribed for Hunter syndrome. It provides a certain enzyme (iduronate-2-sulfatase) to the body. When it is not to be taken (Contraindications): Hypersensitivity.
Dosage & When it is to be taken :
IV- The recommended dosage regimen is 0.5 mg/kg of body weight administered every week as an intravenous infusion. How it should be taken :
It comes as a solution for injection to be administered by a healthcare professional into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of fever, lung or breathing problems, respiratory tract infection, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
Side Effects :
Most Serious- Anaphylactic and allergic reactions.
Most Common- Irregular heart beat, blood clot in lungs, blue or purple coloration of the skin, respiratory failure, infection, joint pain, headache, fever, rash, itching, redness, hives and high blood pressure.
Central Nervous System- Uneasiness, anxiety and irritability.
*Avoid excess dosage. Storage Conditions :
Store it in refrigerator (2°C to 8°C), do not freeze it.
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