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Idarubicin

Latest prescription information about Idarubicin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Idarubicin
Pronunciation : eye-duh-ROO-bih-sin
Therapeutic Classification : Chemotherapy
Trade Name(s): 
India- Zavedos.
International- Idamycin.
Why it is prescribed (Indications) : This medication is an anthracycline antileukemia agent, prescribed for acute myeloid leukemia (AML). It inhibits activities of cancer cells.
When it is not to be taken (Contraindications): Hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : IV- The recommended dose is 12 mg/m² daily for 3 days by slow (10 to 15 min) infusion in combination with cytarabine.
How it should be taken : It comes as a solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of anemia, heart, liver, or kidney problems; bone marrow depression, infection, poor immunity, any allergy, who are taking this medications, children, elderly, during pregnancy and breastfeeding.
* It may reduce platelet counts; avoid injury or bruising.
* Avoid contact with people who have infections.
* Avoid live vaccination during treatment period.
Side Effects : 
Most Common - Infection, nausea, vomiting, hair loss, abdominal cramps, diarrhea, mental illness, fever, headache, nerve disease, lung allergy and seizures.
Heart - Heart failure, chest pain and heart attack.
Skin - Hair loss, rash, hives and redness.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at controlled room temperature (15 to 30°C).

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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