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Ibutilide

Latest prescription information about Ibutilide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Ibutilide
Pronunciation : eye-BYOO-tih-lide
Therapeutic Classification : Antiarrhythmics
ICD Code : Y52.2
Trade Name(s): 
International- Covert.
Why it is prescribed (Indications) : This medication is an antiarrhythmic agent, prescribed for irregular heart rhythm. It works by slowing the conduction of the irregular heartbeat.
When it is not to be taken (Contraindications): It is contraindicated in patients who are taking itraconazole, prolonged QT interval and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : IV- Initial dose: For patients weighing >= 60 Kg: 1 mg administered slowly over 10 minutes infusion. For patients weighing < 60 Kg: 0.01 mg/kg administered slowly over 10 minutes infusion.
How it should be taken : It comes as a solution for injection, to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of heart diseases, low level of minerals in blood, any allergy, who are taking other medications, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness, drowsiness, or blurred vision, do not drive a car or operate machinery while taking this medication.
Side Effects : 
Heart- Low/high blood pressure, palpitations, slow/fast heart rate, heart failure and fainting.
Gastrointestinal - Nausea.
Central Nervous System- Headache.
Other Precautions : 
*Avoid excess dosage.
Storage Conditions : 
Store it at controlled room temperature (20° to 25°C).

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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