Information about Ibritumomab Tiuxetan

Generic Name : Ibritumomab Tiuxetan
Up-to-date prescription details regarding Ibritumomab Tiuxetan are provided here.

Pronunciation : EYE-bri-TOOM-oh-mab tye-UX-e-tan/IN-dee-um

Learn the correct pronunciation of the Ibritumomab Tiuxetan, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y43.3 Therapeutic Classification : Chemotherapy

Trade Names/Brand Names of Ibritumomab Tiuxetan

International :

Zevalin Kit-Indium-111

Why is Ibritumomab Tiuxetan Prescribed? (Indications)

This medication is a monoclonal antibody, prescribed for non-Hodgkin's lymphoma with other medications. It works by killing certain blood and cancer cells from body immune system.

When should Ibritumomab Tiuxetan not be taken? (Contraindications)

Contraindicated in patients with bone marrow depression and hypersensitivity.

What is the dosage of Ibritumomab Tiuxetan?

Adults- IV- Step 1: Infuse rituximab 250 mg/m 2 at a rate of 50 mg/h, escalate the dose up to 400mg/hr. After this administer indium-111 (In-111) ibritumomab tiuxetan 5 mCi (1.6 mg total antibody dose) administered as a 10-min IV push.
Step 2: Continue this procedure for 7 to 9 days.

How should Ibritumomab Tiuxetan be taken?

It comes as a solution for injection to be administered by a healthcare provider into the vein.

What are the warnings and precautions for Ibritumomab Tiuxetan?

• Caution should be exercised in patients with history of blood disorders, decrease in complete blood cell counts due to bone marrow depression, any allergy, who are taking other medications, during pregnancy and breastfeeding.

• It may cause dizziness, do not drive a car or operate machinery while taking this medication.

• It may reduce platelet counts; avoid injury or bruising.

• Avoid contact with people who have infections.

• Patient may develop with increased the risk of certain blood cancers; consult with your doctor before taking this medication.

• Avoid live vaccination during the treatment period.

• Monitor complete blood counts regularly while taking this medication.

What are the side effects of Ibritumomab Tiuxetan?

Most Common - Reduction in the number of blood cells, fatigue, abdominal pain, nausea, cold, weakness, diarrhea, cough and fever.
Body as a Whole - Influenza-like illness.
Musculoskeletal - Muscle pain and loss of appetite.
Respiratory - Cough, throat pain, upper respiratory tract infection and nosebleed.
Central Nervous System - Dizziness.
Heart - High blood pressure.
Skin - Night sweats, blister, itching and rash.
Genitourinary - Urinary tract infection.