Hydrochlorothiazide and Triamterene - Drug Information

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General Information on Hydrochlorothiazide and Triamterene

Generic Name : Hydrochlorothiazide and Triamterene

Pronunciation : hye droe klor oh thye' a zide - trye am' ter een

Latest prescription information about Hydrochlorothiazide and Triamterene. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y54.5 | Therapeutic Classification : Diuretics

Trade Names/Brand Names of Hydrochlorothiazide and Triamterene

International- Dyazide, Maxzide.

Why is Hydrochlorothiazide and Triamterene Prescribed? (Indications)

This combination medication contains potassium-sparing diuretic and thiazide diuretic, prescribed for essential hypertension, and edema due to low potassium level in body. It eliminates salt (sodium) and water from the body.

When should Hydrochlorothiazide and Triamterene not to be taken? (Contraindications)

Contraindicated in patients with urination problem, who are taking potassium-sparing agents and hypersensitivity.

Pregnancy Category

A B C D X

Category C :

Animal studies have shown adverse effects on the fetus and there are no appropriate studies in pregnant women, but potential benefits may allow the use of the drug in pregnant women despite the potential for risks.

What is the dosage of Hydrochlorothiazide and Triamterene?

Adult- PO- The recommended dose is 1-2 tablets or capsules daily (25mg/37.5mg). The maximum dose is 75/50 mg daily.

How should Hydrochlorothiazide and Triamterene be taken?

It comes as a tablet and capsule to take by mouth, with or without food.

What are the warnings and precautions for Hydrochlorothiazide and Triamterene?

Caution should be exercised in patients with history of cirrhosis or liver problems, diabetes, gout, kidney problems or kidney stones, skin disorder, any allergy, who are taking other medications, during pregnancy and breastfeeding.
It may cause dizziness, lightheadedness or fainting, do not drive a car or operate machinery while taking this medication and get up slowly from bed while taking this medication.
Avoid exposure to sunlight; otherwise it may cause sunburn easily.
In diabetic patients it may affect blood sugar level; monitor sugar level regularly.
Monitor liver function, kidney function, lung function, blood pressure regularly while taking this medication.

What are the side effects of Hydrochlorothiazide and Triamterene?

   Hypersensitivity : Shock, rash, hives, redness of the skin and photosensitivity.
   Heart : Abnormal heart rhythm and low blood pressure.
   Metabolic : Increased sugar and acidity.
   Gastrointestinal : Jaundice and/or liver enzyme abnormalities, inflammation of pancreas, nausea, vomiting, diarrhea, constipation and abdominal pain.
   Genitourinary : Kidney failure.
   Blood : Decrease in white blood cells and platelets, anemia and bruising.
   Musculoskeletal : Muscle cramps.
   Central Nervous System : Weakness, fatigue, dizziness, headache and dry mouth.
   Miscellaneous : Impotence.

What are the other precautions for Hydrochlorothiazide and Triamterene?

Avoid excess dosage.

What are the storage conditions of Hydrochlorothiazide and Triamterene?

Store it at controlled room temperature (20 to 25C), and in an airtight container. Keep away from children.

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