|
Generic Name : Hydrochlorothiazide and Spironolactone
Pronunciation : hye droe klor oh thye' a zide- speer on oh lak' tone
Therapeutic Classification : Diuretics
ICD Code : Y54.5
Trade Name(s): International- Aldactazide, Spironazide, Spirozide. Why it is prescribed (Indications) : This combination medication contains potassium-sparing diuretic and thiazide diuretic, prescribed for essential hypertension and fluid retention caused by various conditions, including heart disease. When it is not to be taken (Contraindications): Contraindicated in patients with anuria, acute kidney impairment and hypersensitivity.
Dosage & When it is to be taken : Po- The recommended dose is 100mg (Hydrochlorothiazide 100mg and Spironolactone 100mg) in a single dose or in divided dose. How it should be taken : It comes as a tablet to take by mouth, with or without food. Warnings and Precautions : * Caution should be exercised in patients with diabetes, gout, kidney or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding. * It may cause dizziness, do not drive a car or operate machinery while taking this medication. * Avoid alcohol consumption. * Avoid exposure to sunlight; otherwise it may cause sunburn. * It may affect blood sugar level; monitor sugar level regularly. * Monitor liver function, kidney function, lung function, blood pressure, blood electrolytes and fasting blood glucose levels regularly while taking this medication. Side Effects : Body as a whole - Weakness. Heart - Low blood pressure. Gastrointestinal - Inflammation of pancreas, jaundice, diarrhea, vomiting, cramping, constipation, gastric irritation, nausea and loss of appetite. Blood - Anemia and decrease in white blood cells/platelets. Hypersensitivity - Shock, respiratory distress including lung inflammation/swelling, photosensitivity, fever, hives, rash and bruising. Metabolic - Electrolyte imbalance. Musculoskeletal - Muscle spasm. Central Nervous system - Vertigo, tingling, dizziness, headache and restlessness. Genitourinary - Kidney failure. Skin - Redness and itching. Eye - Blurred vision. * Avoid excess dosage. Storage Conditions : Store it in room temperature (25°C). |
![]() Comment & Contribute
![]()
![]() ![]() | ||



Ask an Expert