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Hydralazine

Latest prescription information about Hydralazine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Hydralazine
Pronunciation : hye dral' a zeen
Therapeutic Classification : Vasodilators
ICD Code : Y52.3
Trade Name(s): 
India- Isolazine.
International- Apresoline, Dralzine.
Why it is prescribed (Indications) : 
This medication is a smooth muscle relaxant, prescribed for essential hypertension. This medication lowers the blood pressure.  
When it is not to be taken (Contraindications): 
Hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Initial: The recommended dose is 10 mg four times daily for the first 2-4 days, increase to 25 mg four times daily for the balance of the first week.
How it should be taken : 
It comes as a tablet to take by mouth, as directed by your physician.
Warnings and Precautions : 
* Caution should be exercised in patients with history of heart disease, kidney or liver disease, heart attack, any allergy, who are taking other medications, children, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* Monitor complete blood counts, blood pressure and antinuclear antibody titers while taking this medication.
Side Effects : 
Common - Headache, loss of appetite, nausea, vomiting, diarrhea, palpitations, fast heart rate and chest pain.
Less Frequent
Gastrointestinal - Constipation and intestinal obstruction.
Heart - Low blood pressure and swelling.
Respiratory - Difficulty in breathing.
Central Nervous System - Tingling, numbness, dizziness, tremors, muscle cramps, depression, disorientation and anxiety.
Genitourinary - Difficulty in urination.
Blood - Anemia and decrease in white blood cells.
Hypersensitivity - Rash, hives, itching, fever, chills, joint pain and eosinophilia.
Miscellaneous - Nasal congestion, flushing, lacrimation and eye inflammation.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature, and in an airtight container.

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Member Comments ( 2 )
Should 25mg Hydralazine 3x day be taken with 40mg Furosamide x2 day
as well as Clonidine HCL 4x day?
This seems like more than necessary
diuretics for 72yr.old woman that
isn't storing excessive water, but
has Labile Hypertention. Please advise. Thanx

(Posted by Nancy Dave, United States Date : 12/15/2008 )
Dose of Hydralazine Injection not mentioned? Please email me
(Posted by Pradeep pathak, India Date : 1/13/2007 )

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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