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Generic Name : Histrelin acetate
Pronunciation : hiss-TREL-in AS-e-tate
Trade Name(s):
International- Vantas, Supprelin LA. This medication is an analog of gonadotropin-releasing hormone (GnRH), prescribed for children with central precocious puberty and also for hormone-sensitive cancers of the prostate in men and uterine fibroids in women. When it is not to be taken (Contraindications):
When it is to be taken : Adults (Supprelin LA – 2 years of age and older)- Subcutaneous- 1 implant (50 mg) for 12 months. How it should be taken : It comes as a solution for injection to be administered by a healthcare provider under the skin. Special Instruction : * Caution should be exercised in patients with any allergy, who are taking other medications, children, during pregnancy and breastfeeding. * Avoid using contaminated solution of this medication. * It should not be used in children aged less than 2 years. Side Effects : Heart- Palpitations and irregular heart beat. Central Nervous System- Fatigue, headache, sleeplessness, decreased libido, depression, dizziness, irritability, lethargy, uneasiness, tremor and weakness. Skin- Increased sweating, night sweats and itching. Gastrointestinal- Constipation, abdominal discomfort and nausea. Genitourinary- Kidney impairment, impotence, breast enlargement in males, blood in urine, urinary frequency, breast pain, breast tenderness, painful urination, genital itching and kidney stones. Blood- Anemia, bruising and blood clots. Liver- Liver disorder. Local- Implant-site reactions, scar, pain and wound infections. Metabolic- Increased weight, fluid retention, increased appetite and swelling in the extremities. Musculoskeletal- Aggravated back pain, bone pain, muscle twitching, neck pain and pain in limb. Respiratory- Difficulty in breathing. Miscellaneous- Hot flashes, exacerbated pain, feeling cold and flushing. *Avoid excess dosage. Storage Conditions : Store it in refrigerator (2-8ºC). |
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