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Halofantrine

Latest prescription information about Halofantrine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Halofantrine
Pronunciation : ha-loe-FAN-trin
Therapeutic Classification : Anti- Malarials
ICD Code : Y41.2
Trade Name(s): 
International- Halfan.
Why it is prescribed (Indications) : 
This medication is an antimalarial agent, prescribed for malaria. 
When it is not to be taken (Contraindications): 
Contraindicated in patients with a known hypersensitivity and QTC prolongation.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
The recommended dose is 500 mg every 6 hours for 3 doses (total first course dosage 1,500 mg).
How it should be taken : 
It comes as a tablet to take by mouth, on an empty stomach, at least 1 hour before or 2 hours after a meal.
Warnings and Precautions : 
* Caution should be exercised in patients with history of heart problems, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* It should not be used in children.
* Avoid exposure to sunlight.
Side Effects : 
Gastrointestinal - Abdominal pain, loss of appetite, diarrhea, nausea, vomiting.
Central Nervous System - Dizziness, headache.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature, between (20° and 25°C).

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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