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Guanethidine Monosulfate

Latest prescription information about Guanethidine Monosulfate. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Guanethidine Monosulfate
Pronunciation : gwahn-ETH-ih-deen MAH-no-SULL-fate
Therapeutic Classification : anti- adrenergic blockers - peripherally acting
Trade Name(s): 
International- Ismelin.
Why it is prescribed (Indications) : 
This medication is an antihypertensive, prescribed for severe hypertension either alone or with other medications.

When it is not to be taken (Contraindications): 


Contraindicated in patients with heart failure, pheochromocytoma (neuroendocrine tumor), who are taking monoamine oxidase (MAO) inhibitors and hypersensitivity.


When it is to be taken : 
Adults- The recommended initial dose 10 or 12.5 milligrams (mg) once a day.
Children- PO- 0.2 mg/kg/24 h (6 mg/m 2 /24 h ) as single oral dose initially.
How it should be taken : 
It comes as a tablet to take by mouth, with or without food.
Special Instruction : 
* Caution should be exercised in patients with asthma, heart disease, fever, low blood pressure, ulcer, kidney or liver impairment, elderly, children, during pregnancy and breastfeeding.
* It may cause dizziness or blurred vision, lie down or get up slowly from bed.
* Avoid alcohol consumption while taking this medication.
* Avoid abrupt withdrawal.
* Monitor blood pressure, heart and liver function regularly while taking this medication.
Side Effects : 
Gastrointestinal - Diarrhea, vomiting, nausea, increased bowel movements, dry mouth, and parotid tenderness.
Heart - Chest pain, slow heart rate, fluid retention, and heart failure.
Respiratory - Difficulty in breathing, asthma and nasal congestion.
Central Nervous System - Fainting, dizziness, blurred vision, tremor, ptosis of the lids, depression, tingling, weakness, lassitude, and fatigue.
Musculoskeletal - Muscle pain.
Genitourinary - Rise in BUN, urinary incontinence, inhibition of ejaculation, nighttime urination.
Metabolic - Weight gain.
Skin - Skin inflammation, and scalp hair loss.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it in airtight container at room temperature.

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