Golimumab - Drug Information

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General Information on Golimumab

Generic Name : Golimumab

Pronunciation : goe-LIM-ue-mab

Latest prescription information about Golimumab. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
ICD Code : Y43.4 | Therapeutic Classification : Monoclonal antibodies

Trade Names/Brand Names of Golimumab

International- Simponi.

Why is Golimumab Prescribed? (Indications)

This medication is a tumor necrosis factor (TNF) blocker, prescribed for rheumatoid arthritis, ankylosing spondylitis, moderate to severe ulcerative colitis either alone or with other medications.  It blocks a protein named as TNF-alpha in the body

When should Golimumab not to be taken? (Contraindications)

Contraindicated in patients with severe infection, using another TNF blocker and hypersensitivity.

Pregnancy Category

A B C D X

Category B :

Animal studies have failed to demonstrate a risk to the fetus and appropriate studies on pregnant women are lacking.

What is the dosage of Golimumab?

SC- The recommended dose is 50 mg monthly.

How should Golimumab be taken?

It comes as a solution for injection to be administered by a healthcare provider under the skin.

What are the warnings and precautions for Golimumab?

Caution should be exercised in patients with history of tuberculosis, jaundice, heart problem, sugar, HIV, cancer, tingling, nervousness, autoimmune disorder, blood disorder, who are taking other medication, any allergy, elderly, children, during pregnancy and breastfeeding.
It may cause dizziness or vision problem, do not drive a car or operate machinery while taking this medication.
Avoid excess dosage.
Change injection sites.
Patient may develop with increased risk of blood cancer with the following symptoms: unusual bruising, unusual lumps or swelling, unusual tiredness or weakness, weight loss. If it is so consult with your doctor.
It may reduce platelet counts; avoid bruising or injury while taking this medication.

What are the side effects of Golimumab?

  Most Serious: Severe infection and tumor.
  Respiratory: Upper respiratory tract infection/inflammation.
  Liver: Increased liver enzymes level.
  Local: Redness.
  Heart: High blood pressure.
  Central Nervous System: Dizziness and tingling.
  Miscellaneous: Sarcoidosis.

What are the other precautions for Golimumab?

Avoid vaccination while taking this medication.
Monitor liver function, complete blood count regularly while taking this medication.

What are the storage conditions of Golimumab?

Store it in refrigerator (2C to 8C) and in an airtight container.

♦ Safety Labeling Changes Approved By FDA

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