Medindia » Medication Manual » Glucarpidase Injection

Glucarpidase Injection

Latest prescription information about Glucarpidase Injection. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email print Print Save this page Save Syndicate Syndicate
Generic Name : Glucarpidase Injection
Therapeutic Classification : Enzymes
ICD Code : Y43.6
Trade Name(s): 
International- Voraxaze.
Why it is prescribed (Indications) : 
This medication is a carboxypeptidase enzyme, prescribed for reducing methotrexate toxic level in kidney failure patients. It converts methotrexate into an inactive substance.
When it is not to be taken (Contraindications): 
None.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
IV- The recommended dose is 50 Units per kg as a single dose.
How it should be taken : 
It comes as a powder (diluted with fluid) for injection, to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of liver or kidney impairment, any allergy, elderly, children, during pregnancy and breastfeeding.
Side Effects : 
Tingling, flushing, nausea, vomiting, headache, low blood pressure, blurred vision, diarrhea, hypersensitivity, high blood pressure, rash, throat irritation.
Other Precautions : 
* Avoid excess dosage.

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z