Generic Name : Glucarpidase Injection Therapeutic Classification : Enzymes ICD Code : Y43.6
International- Voraxaze. Why it is prescribed (Indications) :
This medication is a carboxypeptidase enzyme, prescribed for reducing methotrexate toxic level in kidney failure patients. It converts methotrexate into an inactive substance. When it is not to be taken (Contraindications):
Dosage & When it is to be taken :
IV- The recommended dose is 50 Units per kg as a single dose. How it should be taken :
It comes as a powder (diluted with fluid) for injection, to be administered by a healthcare provider into the vein. Warnings and Precautions :
* Caution should be exercised in patients with history of liver or kidney impairment, any allergy, elderly, children, during pregnancy and breastfeeding. Side Effects :
Tingling, flushing, nausea, vomiting, headache, low blood pressure, blurred vision, diarrhea, hypersensitivity, high blood pressure, rash, throat irritation.
* Avoid excess dosage.
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