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Glipizide - Indications, Dosage, Side Effects and Precautions

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Information about Glipizide

Generic Name : Glipizide
Up-to-date prescription details regarding Glipizide are provided here.

Pronunciation : GLIP-i-zide

Learn the correct pronunciation of the Glipizide, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y42.3 Therapeutic Classification : Antidiabetics

Trade Names/Brand Names of Glipizide

India :

International :


Glucotrol

Why is Glipizide Prescribed? (Indications)

This medication is a sulfonylurea antidiabetic agent, prescribed for type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood), particularly in people whose diabetes cannot be controlled by diet alone. It increases the amount of insulin secretion and thus regulates the sugar level in the blood.

When should Glipizide not be taken? (Contraindications)

Contraindicated in patients with hypersensitivity, Type 1 diabetes, ketoacidosis, severe kidney or liver impairment, pregnancy and breastfeeding.

What is the dosage of Glipizide?

PO: Initial-2.5 to 5 mg/day as a single dose may increase slowly. Doses greater than 15 mg may be given in 2 divided doses. Max: 40 mg/day.

How should Glipizide be taken?

Extended-release: Should be taken with food. (Swallow whole, do not chew/ crush/ divide.)
Immediate-release: Should be taken on an empty stomach. (Take ½ hour before meals.)

What are the warnings and precautions for Glipizide?

•Caution should be exercised in patients with history of liver, blood disorder.

• Do not drink alcohol while you are taking this medication. It may increase the risk of low blood sugar.

• It may increase the risk of death from heart disease, thyroid problem, moderate liver or kidney failure.

• Monitor blood glucose concentration.

What are the side effects of Glipizide?

Metabolic- Low blood sugar.
Heart- Increased risk of death due to heart problems.
Central Nervous System- Dizziness and vertigo.
Skin- Allergic skin reactions, inflammation of skin, itching, redness, hives, eruptions and photosensitivity.
Eye and ENT- Tinnitus.
Gastrointestinal- GI disturbances (eg, nausea, loss of appetite, heartburn) and diarrhea.
Genitourinary- Mild urinary frequency, elevated Blood, Urea, Nitrogen and creatinine levels.
Liver- Jaundice and elevated LFT (liver function test) results.
Blood- Decrease in white blood cells, platelets, hemoglobin.
Miscellaneous- Disulfiram – like reaction (symptoms like uneasiness, vomiting, mental confusion, chest pain, headache etc on taking alcohol while on the medication), weakness, tingling, fatigue and uneasiness.

What are the other precautions for Glipizide?

Proper diet, regular exercise needed. Do not change the dose of your medicine without checking with your doctor.

What are the storage conditions for Glipizide?

Store it at room temperature and away from excess heat and moisture. Keep in an airtight container and keep away from children.
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