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Glipizide

Latest prescription information about Glipizide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Glipizide
Pronunciation : GLIP-i-zide
Therapeutic Classification : antidiabetics
Trade Name(s): 
India- Bimode Sr Tab, D-Glip Tab, Diacon Tab, Diaglip Tab, Dibizide Tab, Glez Tab, Glibetic Tab, Glide Tab, Glip Tab, Glipiriv Tab, Glipy Tab, Glucolip Tab, Glucotrol Tab, Glylin-5 Tab, Glynase Extentab, Glynase Tab, Glytop Sr Sr-Tab, Glyzip Cr Tab, Glyzip Tab, Godde Tab, G-Trol Sr-Tab, G-Trol Tab, Lipi Tab, Semi-Glynase Tab, Tranase Tab.
International- Glucotrol.
Why it is prescribed (Indications) : 
This medication is a sulfonylurea antidiabetic agent, prescribed for type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood), particularly in people whose diabetes cannot be controlled by diet alone. It increases the amount of insulin secretion and thus regulates the sugar level in the blood.

When it is not to be taken (Contraindications): 


Contraindicated in patients with hypersensitivity, Type 1 diabetes, ketoacidosis, severe kidney or liver impairment, pregnancy and breastfeeding.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
PO: Initial-2.5 to 5 mg/day as a single dose may increase slowly. Doses greater than 15 mg may be given in 2 divided doses. Max: 40 mg/day.
How it should be taken : 
Extended-release: Should be taken with food. (Swallow whole, do not chew/ crush/ divide.)
Immediate-release: Should be taken on an empty stomach. (Take ˝ hour before meals.)
Special Instruction : 
*Caution should be exercised in patients with history of liver, blood disorder.
*Do not drink alcohol while you are taking this medication. It may increase the risk of low blood sugar.
*It may increase the risk of death from heart disease, thyroid problem, moderate liver or kidney failure.
*Monitor blood glucose concentration.
Side Effects : 
Metabolic- Low blood sugar.
Heart- Increased risk of death due to heart problems.
Central Nervous System- Dizziness and vertigo.
Skin- Allergic skin reactions, inflammation of skin, itching, redness, hives, eruptions and photosensitivity.
Eye and ENT- Tinnitus.
Gastrointestinal- GI disturbances (eg, nausea, loss of appetite, heartburn) and diarrhea.
Genitourinary- Mild urinary frequency, elevated Blood, Urea, Nitrogen and creatinine levels.
Liver- Jaundice and elevated LFT (liver function test) results.
Blood- Decrease in white blood cells, platelets, hemoglobin.
Miscellaneous- Disulfiram – like reaction (symptoms like uneasiness, vomiting, mental confusion, chest pain, headache etc on taking alcohol while on the medication), weakness, tingling, fatigue and uneasiness.
Other Precautions : 
*Proper diet, regular exercise needed. Do not change the dose of your medicine without checking with your doctor.
Storage Conditions : 
Store it at room temperature and away from excess heat and moisture. Keep in an airtight container and keep away from children.

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