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Glibenclamide and Metformin

Latest prescription information about Glibenclamide and Metformin. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Glibenclamide and Metformin
Pronunciation : GLY-BEN-CLA-AMIDE +MetFORE-min
Trade Name(s): 
India- Aviglen Fo, Aviglen-Mf, Benclamet, Benformin, Ben-Q-Met, Clamet, Clamet-C, Mide Plu, Combidos, Cuben-M, Daocon-M, Daonil-M, Diabetrol, Diatrac-M, Diolin-M, Dior Plus, Duotrol-Sr, Eumet-D, G-Formin, G-Formin-F, G-Formin-P, Glibact-M, Glibomet, Glibomet F, Glifil M F, Glinil-M, Glitrac-M, Glucomin-P, Gluconil-M, Glucored, Glucored F, Glucotrac, Glutowin F, Glycurb, Iscept. Iscept For, Iscpet 500, Iscept-L, Iscept-P, Melitus, Metclam, Metclam Fo, Metica G, Sugatrol, Sugatrol F, Sugnl-M, Triglycome.
International- Glucovance.
Why it is prescribed (Indications) : 
This medication contains sulfonylurea and biguanide antidiabetic combination, prescribed for type 2 diabetes.

When it is not to be taken (Contraindications): 


Contraindicated in patients with severe kidney disease, chronic metabolic acidosis, diabetic ketoacidosis, with or without coma, and hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.


When it is to be taken : 
Adult: PO- Per tab contains glibenclamide 1.25 mg and metformin 250 mg. As initial therapy: Start with 1 tab 1-2 times/day. It may be increased if needed.
How it should be taken : 
It comes as a tablet to take by mouth, with food.
Special Instruction : 
* Caution should be exercised in patients with history of heart attack, heart, pituitary, or thyroid disease; adrenal insufficiency, stomach problem, infection, glucose-6-phosphate dehydrogenase (G6PD) deficiency, chronic metabolic acidosis, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* Follow the diet and exercise program as directed by your physician.
* During hot season this medication may lead to dehydration; to avoid this problem drink adequate fluid.
* Monitor kidney and liver function, fasting blood glucose, hemoglobin A1c, and complete blood cell counts regularly while taking this medication.
* Extreme caution needed in children less than 6 years old.
Side Effects : 
Low blood sugar, upper respiratory tract infection, diarrhea, headache, nausea/vomiting, abdominal pain and dizziness.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature and in an airtight container.

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