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Glatiramer

Latest prescription information about Glatiramer. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Glatiramer
Pronunciation : gla tir' a mer
Therapeutic Classification : Immunomodulators
Trade Name(s): 
International- Copaxone.
Why it is prescribed (Indications) : 
This medication is an immunomodulator, used to treat multiple sclerosis. It stops the body from damaging its own nerve cells. 
When it is not to be taken (Contraindications): 
Hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
SC: The recommended dose is 20mg/day.
How it should be taken : 
It comes as a solution to inject under the skin (subcutaneously) by a healthcare provider, once a day.
Warnings and Precautions : 
* Patient may experience with the following symptoms: flushing, chest pain, pounding heartbeat, anxiety, trouble in breathing, closing of the throat, and hives. If any of these symptoms become severe, consult with your doctor.
* Caution should be exercised in patients with history of liver or kidney disease, during pregnancy and breastfeeding.
Side Effects : 
Most Common- Injection site reaction, dilatation of blood vessels, rash, runny nose, difficulty in breathing and chest pain.
Heart- Palpitation and fast heart rate.
Eye - Eye disorder and double vision.
Gastrointestinal - Nausea, vomiting and difficulty in swallowing.
Local Reaction - Redness, itching and inflammation.
Hypersensitivity - Influenza, inflammation of nose, bronchus, stomach and vaginal fungal infection.
Metabolic - Increase in weight.
Musculoskeletal - Back pain and benign skin cancer.
Central Nervous System - Tremor, headache, fainting, abnormal thinking, speech disorder, psychiatric disorder, anxiety and nervousness.
Genitourinary- Urinary urgency and painful menstruation.
Respiratory- Cough and spasm.
Skin - Itching, rash and hives.
ENT- Ear pain.
Miscellaneous- Chills, loss of appetite, fever and swelling in the face and leg region.
Other Precautions : 
*Avoid excess dosage.
Storage Conditions : 
Keep it in refrigerator (2°C to 8°C); do not freeze it.


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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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