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Galsulfase

Latest prescription information about Galsulfase. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Galsulfase
Pronunciation : gal-SUL-fase
Therapeutic Classification : Endocrine and Metabolic Agents
Trade Name(s): 
International- Naglazyme.
Why it is prescribed (Indications) : 
This medication is an enzyme, prescribed for Mucopolysaccharidosis VI. It helps to decrease a substance, which causes problem in the body.
When it is not to be taken (Contraindications): 
Hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
IV- The recommended dose is 1 mg per kg of body weight administered once weekly.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with history of fever, lung or breathing disease, difficulty in breathing during sleep, oxygen deficiency, any allergy, who are taking other medications, children less than 5 years old, during pregnancy and breastfeeding.
Side Effects : 
Most Common - Difficulty in breathing, fever, chills, chest pain and respiratory distress.
Gastrointestinal - Abdominal pain and naval hernia.
Miscellaneous - Joint pain, eye inflammation, uneasiness, hearing impairment and rash.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it under refrigeration (2° to 8°C). Do not freeze it.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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