Generic Name : Gadoversetamide Injection Therapeutic Classification : Diagnostic Agents ICD Code : Y57.6
International- OptiMARK. Why it is prescribed (Indications) :
This medication is a gadolinium-based MRI contrast agent, used for cranial, spinal and whole body imaging in patients with an abnormal blood brain barrier or abnormal vascularity of the brain, and liver structural abnormalities. When it is not to be taken (Contraindications):
Contraindicated in patients with severe kidney disease, acute kidney injury, and hypersensitivity.
Dosage & When it is to be taken :
IV bolus- The recommended dose is 0.2 mL/kg (0.1 mmol/kg) and at a rate of 1 to 2 mL/sec delivered by manual or by power injection. How it should be taken :
It comes as a solution for injection, to be administered by a healthcare provider into the vein. Warnings and Precautions :
* Caution should be exercised in children, elderly, during pregnancy and breastfeeding. Side Effects :
Body as a Whole - Headache, abdomen pain, weakness, back pain, allergic reaction, face swelling, fever, flu-like syndrome, uneasiness, neck rigidity, neck pain, pelvic pain, and increased sweating.
Heart - Dilatation of blood vessels, abnormal heart rhythm, chest pain, high or low blood pressure, palpitations, fainting and fast heart beat.
Gastrointestinal - Nausea, diarrhea, indigestion, loss of appetite, increased appetite, constipation, dry mouth, difficulty in swallowing, eructation, flatulence, increased salivation, thirst and vomiting.
Blood - Decrease in platelet counts.
Metabolic - Fluid retention, increased level of blood sugar and calcium.
Musculoskeletal - Joint pain, leg cramps, muscle pain, and spasm.
Central Nervous System - Dizziness, tingling, agitation, anxiety, confusion, depersonalization, double vision, hallucinations, increased muscle tone, nervousness, drowsiness, tremor and fainting.
Respiratory - Runny nose, asthma, cough, difficulty in breathing, nosebleed, blood vomiting, and voice alteration.
Skin - Application site reaction, swelling in the injection site, redness of the skin, itching, rash, skin dry, inflammation injection site, and hives.
Eye and ENT - Taste perversion, abnormal vision, eye inflammation, and ringing in the ear.
Genitourinary - Difficulty in urination and urine frequency.
*Avoid excess dosage. Storage Conditions :
Store it at controlled room temperature (20°C to 25°C).
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