Gadoterate meglumine - Drug Information

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Generic Name : Gadoterate meglumine

Latest prescription information about Gadoterate meglumine. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Trade Names/Brand Names : 

International- Dotatrem.

Why it is prescribed : 

This medication is a gadolinium based contrast agent, prescribed for visualization of brain along with with magnetic resonance imaging (MRI).  

When it is not to be taken (Contraindications): 

Contraindicated in patients with hypersensitivity.

Dosage & When it is to be taken (Indications): 

IV- The recommended dose is 0.2 mL/kg, (0.1 mmol/kg) as bolus injection.

How it should be taken : 

It comes as a powder for injection (diluted with fluid) to be administered by a healthcare provider into the vein.

Warnings and Precautions : 

•Caution should be exercised in patients with history of acute kidney injury, impaired elimination of GBCAs, any allergy, who are taking other medications.
• Patient with impaired elimination of GBCAs may experience with increased risk of Nephrogenic Systemic Fibrosis.
• Monitor patients closely for need of emergency breathing support.

Side Effects : 

•  Most frequent: Nausea, headache, injection site pain, injection site coldness and burning sensation.
•  Heart: Abnormal heart rhythm, fast or slow heart rate.
•  Immune System: Hypersensitivity/anaphylactoid reactions including heart arrest, respiratory arrest, blue or purple coloration of the skin or mucous, throat swelling, asthma, eye inflammation, eyelid swelling, increased tears, increased sweating and hives.
•  Central Nervous System: Coma, convulsion, fainting, lightheadedness, smell loss, tremor
•  Musculoskeletal: Muscle contracture, muscle weakness.
•  Gastrointestinal: Diarrhea, increased salivary secretion.
•  General: Uneasiness and fever.
•  Skin: Inflammation of a vein

Other Precautions : 

Avoid excess dosage.

Storage Conditions : 

Store it at controlled room temperature (25°C).


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