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Gadofosveset Trisodium Injection

Latest prescription information about Gadofosveset Trisodium Injection. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Gadofosveset Trisodium Injection
Pronunciation : GAD-oh-FOS-ve-set trye-SOE-dee-um
Therapeutic Classification : Diagnostic Agents
ICD Code : Y57.6
Trade Name(s): 
International- Ablavar.
Why it is prescribed (Indications) : 
This medication is a gadolinium-based MRI contrast agent, used to diagnose peripheral vascular disease.  It helps in clear visualization of blood vessels, organs, and other non-bony tissues.
When it is not to be taken (Contraindications): 
Hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Adult- IV- The recommended dose is 0.12 mL/kg body weight (0.03 mmol/kg) over 30 seconds infusion.
How it should be taken : 
It comes as a solution for injection, to be administered by a healthcare provider into the vein.
Warnings and Precautions : 
* Caution should be exercised in patients with severe kidney disease, muscle weakness, skin disorder, joint stiffness, bone pain, moving trouble, high blood pressure, diabetes, QT prolongation, recent injury, any allergy, during pregnancy and breastfeeding.
* Patient may develop with increased risk of severe kidney problem; if it is so consult with your healthcare provider.
* Monitor kidney and heart functions regularly while taking this medication.
Side Effects : 
Heart - Dilatation of blood vessels and high blood pressure.
Central Nervous System - Headache, tingling, dizziness and fainting.
Gastrointestinal - Nausea and difficulty in swallowing.
Local - Injection-site bruising.
Miscellaneous - Itching, burning sensation and feeling cold.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (25°C). Protect from light and freezing.


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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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