Why it is prescribed :
This medication is an estrogen receptor antagonist, prescribed for advanced breast cancer in postmenopausal women who have already been treated with other medications. It works by degrading the estrogen receptor.
When it is not to be taken (Contraindications):
Contraindicated in women, patients with low platelet count and known hypersensitivity.
Category D :
There is an evidence of fetal risk based on adverse reaction data, but potential benefits may allow the drug to be used in pregnant women despite risks.
Dosage & When it is to be taken (Indications):
IM- The recommended dose is 500 mg to be administered into the buttocks slowly.
How it should be taken :
It comes as a solution for injection to be administered by a healthcare provider into the large muscle.
Warnings and Precautions :
Caution should be exercised in patients with liver impairment, who are taking other medications, any allergy, during pregnancy and breastfeeding.
It may cause dizziness, do not drive a car or operate machinery while taking this medication.
Side Effects :
Body as a Whole
Weakness, pain, back pain, abdominal pain, injection site pain, pelvic pain, chest pain, flu syndrome, fever and accidental injury.
Dilatation of blood vessels.
Nausea, vomiting, diarrhea, loss of appetite.
Swelling in the extremities and elevation of liver enzymes.
Bone pain, joint pain.
Central Nervous System
Dizziness, sleeplessness, tingling, depression, anxiety.
Inflammation of pharynx, difficulty in breathing and increased cough.
Urinary tract infection.
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store it in refrigerator (2�-8�C). Do not freeze it. Protect from light.