Trade Names/Brand Names :
Why it is prescribed :
This medication is a hormonal chemotherapy agent, prescribed for malignant neoplasms. Especially used in the treatment of prostate cancer.
When it is not to be taken (Contraindications):
Category X :
Animal and/or human studies have demonstrated fetal injury and potential risks outweigh the benefits of the drug in pregnancy. These drugs are found to be harmful when taken during pregnancy, and should not be used.
Dosage & When it is to be taken (Indications):
Adult: PO- As Na: 360-480 mg 3 times/day. Maintenance: 120-240 mg 3 times/day. IV- As Na: Initial: 600-1,200 mg/day via slow injection for 5-10 days, then 300 mg/day for 10-20 days.
How it should be taken :
It comes as a tablet to take by mouth, with or without food.
It also comes as a solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions :
• Caution should be exercised in patients with history of heart disease, liver impairment, during pregnancy and breastfeeding.
Slow infusion is not recommended.
Side Effects :
Nausea, fluid retention, arterial and venous thrombosis, impotence, breast enlargement in male, withdrawal bleeding, increase in blood calcium level and bone pain.
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store it at room temperature.