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Fluorouracil

Latest prescription information about Fluorouracil. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Fluorouracil
Pronunciation : flure oh yoor' a sill
Therapeutic Classification : miscellaneous dermatologicals
Therapeutic Classification : Chemotherapy
Trade Name(s): 
India- 5-Flucel Amp, 5fu-Cbc Amp, 5-Fu-Korea Inj, Fivocil Amp, Fivoflu Vial, Flocil Amp, Flonida Cream, Florac Inj, Flucil Inj, Fludin Inj Vial, Fluonco Inj, Fluracil Amp, Fluracil Cap, Flutas Amp, Kucil-50 Amp, Oncofluor Amp, Oncourcil Inj, Tevafluoro Vial, Zypurin Tab.
International- Adrucil, Carac, Efudix, Efudex And Fluoroplex.
Why it is prescribed (Indications) : 
This medication is an antimetabolite, prescribed for certain types of cancer such as colon, rectal, breast, stomach and pancreatic cancer.

When it is not to be taken (Contraindications): 


Contraindicated in patients with severe infection, who are taking sorivudine and hypersensitivity.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
PO- The recommended dose is 1gm on alternate days, then 1 gm weekly. IV- 12mg/kg/day for 4 days.
Topical: 0.5 -5%cream- Apply 1-2 times/day for 2-4 week.
How it should be taken : 
It comes as a tablet to take by mouth. It also comes as a solution for injection to be administered by a healthcare provider into the vein.
Special Instruction : 
* Caution should be exercised in patients with liver or kidney impairment, any allergy, who are taking other medications, during pregnancy and breast-feeding.
* Avoid contact with people who have any infection.
* It may reduce platelet counts; avoid bruising or bleeding.
* Avoid vaccination while taking this medication.
Side Effects : 
Most Common - Burning, crusting, skin inflammation, erosions, redness of the skin, pigmentation, irritation, pain, photosensitivity, itching, scar, rash, soreness and ulceration.
Central Nervous System - Emotional upset, sleeplessness and irritability.
Gastrointestinal - Taste perversion and mouth ulcer.
Blood - Eosinophilia, decrease in platelets and toxic granulation.
Skin - Hair loss, blistering, scaling, swelling, tenderness and hives.
Special Senses - Eye irritation, increased tears and nose irritation.
Miscellaneous - Herpes simplex.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at room temperature (25�C), and in an airtight container. Keep away from children.

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