Information about Fludarabine

Generic Name : Fludarabine
Up-to-date prescription details regarding Fludarabine are provided here.

Pronunciation : floo dare' a been

Learn the correct pronunciation of the Fludarabine, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

Trade Names/Brand Names of Fludarabine

Fludara (50mg) | Fludacel (50 mg) | Fludacel (10 mg) | Fludara (10 mg) | Naprobin (50 mg)

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International :

Fludara Vial, Fludarin Vial

Why is Fludarabine Prescribed? (Indications)

This medication is prescribed for blood cancer(white blood cells) in adults who have already been treated with at least one other medication and have not got better. It is a purine analog. It slows or stops the growth of cancer cells in the body.

When should Fludarabine not be taken? (Contraindications)

Contraindicated in patients with kidney impairment, abnormal breakdown of red blood cells, elderly, pregnancy and lactation.

What is the dosage of Fludarabine?

The recommended dose is 25 mg/ m 2 administered intravenously or 40 mg/m 2 orally over a period of approximately 30 minutes, daily for 5 days every 28 days.

How should Fludarabine be taken?

This medication is available in the form of injection to be injected over 30 minutes intravenously (into the vein) by healthcare providers. It is 28 days cycle with once a day for 5 days in a row may be taken with or without food. Advised to take wholly.

What are the warnings and precautions for Fludarabine?

•Monitor blood counts and hemoglobin concentration regularly.

Monitor for signs of autoimmune abnormal breakdown of red blood cells either in the blood vessels or elsewhere in the body.

• Avoid contact with skin, eyes and respiratory tract.

It may cause drowsiness, dizziness, tiredness, weakness, vision problems, confusion, agitation, or seizures. Do not drive a car or perform other dangerous activities while taking this medication.

Bone marrow suppression may be cumulative and severe increased risk of opportunistic infections.

What are the side effects of Fludarabine?

Central Nervous system- Headache, depression, sleep problems. In high dose it may cause blindness, coma, and death.
Gastrointestinal- Stomach disturbances, loss of appetite, nausea, vomiting, constipation, diarrhea and mouth sore.
Heart- Chest pain and irregular heart beat.
Respiratory-Difficulty in breathing, pneumonia and severe lung toxicity.
Skin- Hair loss, rash, hives and peeling skin.
Miscellaneous- Fever, chills, cough and difficulty in swallowing.