Medindia » Consumer Health » Medication Manual » Fludarabine

Fludarabine

Latest prescription information about Fludarabine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
Email Email Save this page Save Syndicate Syndicate
Generic Name : Fludarabine
Pronunciation : floo dare' a been
Therapeutic Classification : Chemotherapy
Trade Name(s): 
International- Fludara Vial, Fludarin Vial.
Why it is prescribed (Indications) : 
This medication is prescribed for blood cancer(white blood cells) in adults who have already been treated with at least one other medication and have not got better. It is a purine analog. It slows or stops the growth of cancer cells in your body.

When it is not to be taken (Contraindications): 


Contraindicated in patients with kidney impairment, abnormal breakdown of red blood cells, elderly, pregnancy and lactation.

Pregnancy Category :

A B C D X
Category D : There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
The recommended dose is 25 mg/ m 2 administered intravenously or 40 mg/m 2 orally over a period of approximately 30 minutes, daily for 5 days every 28 days.
How it should be taken : 
This medication is available in the form of injection to be injected over 30 minutes intravenously (into the vein) by healthcare providers. It is 28 days cycle with once a day for 5 days in a row may be taken with or without food. Advised to take wholly.
Special Instruction : 
*Monitor blood counts and hemoglobin concentration regularly.
*Monitor for signs of autoimmune abnormal breakdown of red blood cells either in the blood vessels or elsewhere in the body.
* Avoid contact with skin, eyes and respiratory tract.
*It may cause drowsiness, dizziness, tiredness, weakness, vision problems, confusion, agitation, or seizures. Do not drive a car or perform other dangerous activities while taking this medication.
*Bone marrow suppression may be cumulative and severe increased risk of opportunistic infections.
Side Effects : 
Central Nervous system- Headache, depression, sleep problems. In high dose it may cause blindness, coma, and death.
Gastrointestinal- Stomach disturbances, loss of appetite, nausea, vomiting, constipation, diarrhea and mouth sore.
Heart- Chest pain and irregular heart beat.
Respiratory-Difficulty in breathing, pneumonia and severe lung toxicity.
Skin- Hair loss, rash, hives and peeling skin.
Miscellaneous- Fever, chills, cough and difficulty in swallowing.
Other Precautions : 
*Do not receive a live vaccine during the treatment.
Storage Conditions : 
Refrigerate at 2-8°C. Store it in airtight container.

Comment & Contribute
Comments should be on the topic and should not be abusive. Comments are normally moderated and are reviewed after they are posted.
* Your comment can be maximum of 2500 characters
I agree to the terms and conditions
If you have a question about health related issues, you can now post it in our Ask An Expert section on our community website Medwonders.com and get answers from our panel of experts.

Browse the Drugs alphabetically

Drugs Index
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Price List