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Ezetimibe

Updated on : January - 2012
Latest prescription information about Ezetimibe. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Ezetimibe
Pronunciation : ezet-I-mibe
Therapeutic Classification : Antilipemics
ICD Code : Y52.6
Trade Name(s): 
India- Ezedoc, Ezenia, Ezerem, Ezibloc, Ezta, Ezzicad, Lipezet, Mibe, Zeteze, Zetica.
International- Zetia.
Why it is prescribed (Indications) : 
This medication is a lipid-lowering agent, prescribed for hypercholesterolemia. It prevents the absorption of cholesterol in the intestine.
When it is not to be taken (Contraindications): 
Contraindicated in patients with severe liver problem and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
PO- The recommended dose is 10 mg once daily.
How it should be taken : 
It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of liver, thyroid, kidney problems, muscle pain, tenderness, weakness, any allergy, who are taking other medications, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* Follow the diet and exercise program as directed by your healthcare provider.
Side Effects : 
Most Common - Muscle/joint pain, upper respiratory tract infection and diarrhea.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store at room temperature, and in an airtight container.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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