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Medindia » Medication Manual » Exenatide

Exenatide

Latest prescription information about Exenatide. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.

Generic Name : Exenatide

Pronunciation : ex en' a tide

Therapeutic Classification : Antidiabetics

ICD Code : Y42.3

Trade Name(s):
International- Byetta.

Why it is prescribed (Indications) :
This medication is a incretin mimetic, prescribed for type 2 diabetes with diet and exercise, either alone or with other medications. It works by stimulating the pancreas to secrete insulin in hyperglycemic condition.

When it is not to be taken (Contraindications):
Hypersensitivity.

Pregnancy Category :

A B C D X

Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken :
Adult- The initial dose is 5 mcg injected under the skin (subcutaneously) twice daily, 60 minutes before breakfast or dinner.

How it should be taken :
It comes as a solution for injection, to be administered by a healthcare provider under the skin.

Warnings and Precautions :
*Caution should be exercised in patients with history of gallstone disorder, smoking, drinking alcohol, who is taking other medications, any allergy, stomach, heart, liver, or kidney problems, during pregnancy and breastfeeding.
*Patient may develop with low blood sugar, weight loss and decreased appetite; monitor blood sugar regularly while taking this medication.
*It may cause dizziness, lightheadedness, or drowsiness, do not drive a car or operate machinery while taking this medication.

Side Effects :
Most Common- Nausea.
Central Nervous System- Dizziness or lightheadedness, nervousness, mood changes, weakness, shakiness, confusion, epilepsy and loss of consciousness.
Gastrointestinal- Extreme thirst, extreme hunger, stomach upset, vomiting, diarrhea and difficulty in swallowing.
Skin- Rash, hives and itching.
Allergic reactions- Swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs and difficulty in breathing.

Other Precautions :
*If patient is taking oral contraceptives or antibiotics take them one hour before this medication.

Storage Conditions :
Store it in refrigerator (2 to 8Â°C), protect from light. Do not freeze it.