Generic Name : Exemestane Pronunciation : ex e mes' tane Therapeutic Classification : Chemotherapy ICD Code : Y43.3♦ Safety Labeling Changes Approved By FDA
Therapeutic Classification : Chemotherapy Trade Name(s):
India- X'cel Film-Coated Tab, Xtane Tab.
International- Aromasin. Why it is prescribed (Indications) :
This medication is an aromatase inhibitor, prescribed for advanced breast cancer in postmenopausal women who are no longer responsive to anti-estrogen therapy. It works by decreasing the amount of estrogen. When it is not to be taken (Contraindications):
Contraindicated in patients with hypersensitivity, pregnancy and lactation, premenopausal women.
Dosage & When it is to be taken :
PO- The recommended dose is 25 mg once daily. How it should be taken :
This medication available in the form of tablet to take by mouth. It is usually taken once a day after a meal. Warnings and Precautions :
*This medication is only for women who have experienced menopause and cannot become pregnant.
*Inform your doctor about your pregnancy and breastfeeding.
*It may lead to liver or kidney disease.
*Monitor bone mineral density at regular intervals especially in patients at risk of osteoporosis.
* Caution should be exercised in patients with history of liver or kidney problems, osteoporosis (weak bones), heart problems, blood vessel problems, stroke, any allergy, and who are taking other medications. Side Effects :
Heart- Chest pain, hypertension, accumulation of fluids.
Central Nervous System- Fatigue, depression, sleeplessness, anxiety, headache, dizziness.
Skin- Rash, increased sweating, abnormal hair growth, hair loss, and acne.
Hormone- Hot flushes, weight gain.
Gastrointestinal- Low potential for nausea and vomiting, abdominal pain, anorexia, constipation, diarrhea, and increased appetite.
Blood- Abnormally low level of lymphocytes.
Musculoskeletal- Musculoskeletal pain, joint pain.
Respiratory- Difficulty in breathing, coughing.
♦ Miscellaneous- Flu-like symptoms with fever, hoarseness; hypersensitivity, hives and itching.
*Avoid excess dosage. Storage Conditions :
Store at 25Â°C. Store it in airtight container and keep away from children.
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