Why it is prescribed :
This medication is a non-steroidal anti-inflammatory drug (NSAID), prescribed for osteoarthritis, rheumatoid arthritis and gouty arthritis. It blocks a substance in the body named as cyclo-oxygenase-2 (COX-2).
When it is not to be taken (Contraindications):
Contraindicated in patients with peptic ulcer, severe heart disease, stroke, and hypersensitivity.
Category X :
Animal and/or human studies have demonstrated fetal injury and potential risks outweigh the benefits of the drug in pregnancy. These drugs are found to be harmful when taken during pregnancy, and should not be used.
Dosage & When it is to be taken (Indications):
PO- Adult- The recommended dosage is 60 to 120mg once daily.
How it should be taken :
It comes as a tablet to take by mouth, with or without food.
Warnings and Precautions :
Caution should be exercised in patients with history of heart, liver, kidney disease, high blood pressure, blood clotting disorder, any allergy, children, elderly, during pregnancy and breast feeding.
Drink adequate fluid to avoid dehydration.
Stop the medication immediately if gastrointestinal lesions occur.
Monitor blood pressure regularly while taking this medication.
Side Effects :
Central Nervous System
Headache, dizziness, nervousness, depression, drowsiness, insomnia, vertigo and ringing in the ear.
Chest pain, high blood pressure and fluid retention.
Taste disturbances, mouth ulcer, loss of appetite and weight loss.
Kidney damage, fever, GI disorders, muscle pain and influenza-like syndrome.
Other Precautions :
Avoid excess dosage.
Storage Conditions :
Store it in refrigerator.