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Ethionamide - Indications, Dosage, Side Effects and Precautions

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Information about Ethionamide

Generic Name : Ethionamide
Up-to-date prescription details regarding Ethionamide are provided here.

Pronunciation : ETH-eye-ON-a-mide

Learn the correct pronunciation of the Ethionamide, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.
You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.


ICD Code : Y41.1 Therapeutic Classification : Anti- Tuberculosis

Trade Names/Brand Names of Ethionamide

India :

Overview of Ethionamide

• Ethionamide is an antibiotic which is used for the treatment of tuberculosis.

Why is Ethionamide Prescribed? (Indications)

Ethionamide is an antibiotic. It is used for the treatment of tuberculosis as a second-line drug in combination with other drugs, especially in cases of resistance to the standard drugs.

When should Ethionamide not be taken? (Contraindications)

• It is contraindicated in patients allergic to drugs or with severe liver impairment.
• It should not be used in porphyria.

What is the dosage of Ethionamide?

• The recommended adult dose for ethionamide is 5 to 20 mg/kg tablet.
• Start with a low dose and increase over every one to two days to a maximum dose of 1 g/day.

How should Ethionamide be taken?

• Ethionamide should be taken once daily or in divided doses after the meal as directed by the physician.

What are the warnings and precautions for Ethionamide?

• Caution should be taken in patients with diabetes mellitus or kidney disease

• Liver function tests and eye examinations should be conducted on a regular basis during treatment

• Caution should be taken in patients with thyroid dysfunction.

What are the side effects of Ethionamide?

Digestive system: Nausea, vomiting, diarrhea, abdominal pain, stomatitis, loss of appetite
Nervous System: Drowsiness, dizziness, restlessness, psychiatric disturbances, peripheral neuropathy, headache and seizure
Eye: Blurring of vision, double vision, optic neuropathy
Liver: Hepatitis, jaundice
Cardiovascular: Low blood pressure
Others: Skin reactions, impotence, reduced white blood cell and platelet counts, allergic reactions, joint pain

What are the other precautions for Ethionamide?

• Do not use the drug during pregnancy.
• It is important to complete the course of the tuberculosis medicines even if the patient is feeling well.

What are the Drug Interactions of Ethionamide?

• Alcohol may enhance the adverse effect of ethionamide resulting in a psychotic episode.
• Ethionamide should not be taken in combination with cholera or other live vaccines as the antibiotic may diminish the therapeutic effects of the vaccines.
• Ethionamide may increase the side effect of cycloserine.
• Ethionamide may increase the blood level of isoniazid.

What are the storage conditions for Ethionamide?

• It should be stored Store at 20°C to 25°C.
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