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Ethacrynic Acid

Latest prescription information about Ethacrynic Acid. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Ethacrynic Acid
Pronunciation : eth a krin' ik
Therapeutic Classification : Cardiovascular Agents
ICD Code : Y52
Trade Name(s): 
International- Edecrin.
Why it is prescribed (Indications) : 
This medication is a loop diuretic, prescribed for fluid retention caused by heart, liver and severe kidney problems. It helps the kidney to get rid of unwanted water and salt from the body into the urine.
When it is not to be taken (Contraindications): 
It should be discontinued if electrolyte imbalance, progressive kidney disease, decrease in urination occur during the treatment. Contraindicated in patients with hypersensitivity.

Pregnancy Category :

A B C D X
Category B : Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Dosage & When it is to be taken : 
PO- The recommended dose range is 50 to 200 mg daily.
How it should be taken : 
It comes as a tablet to take by mouth, once or twice a day with food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of diabetes, gout or liver disease, any allergy, who are taking other medications, during pregnancy and breastfeeding.
* It may cause dizziness, do not drive a car or operate machinery while taking this medication.
* Avoid alcohol consumption.
* Patient may develop with increased risk of stomach bleeding; if you experience abdominal pain, burning sensation, weight changes, consult with your doctor immediately.
* Avoid exposure to sunlight; otherwise it may cause sensitivity to the sun.
* Monitor blood sugar level regularly while taking this medication.
Side Effects : 
Gastrointestinal - Loss of appetite, uneasiness, abdominal discomfort or pain, difficulty in swallowing, nausea, vomiting, and diarrhea.
Metabolic - Reversible elevated uric acid and acute gout and decrease in blood sugar.
Blood - Decrease in blood cell counts.
Eye and ENT - Deafness, ringing in the ear, unsteadiness and blurred vision.
Central Nervous System - Headache, fatigue, fearness and confusion.
Miscellaneous - Skin rash, fever, chills and blood in urine.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Keep this medication in the container it came in and out of the reach of children.

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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