Estradiol - Drug InformationGeneric Name : Estradiol | Pronunciation : ES-tra-DYE-ol
Latest prescription information about Estradiol. Learn how to pronounce the drug's name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
International :Divigel Gel, E 2 Vaginal Tab Tab, E2 Gel Gel, Estraderm Mx Patch, Estrofem Tab, Ets Patch Patch, Evalon Crm Cream, Evalon Tab, Oestrogel Gel, Progynon Depot Inj, Progynova Tab, Sandrena Gel
Why it is prescribed (Indications) :
This medication is a sex hormone, prescribed for treating conditions due to menopause, treating vulval or vaginal atrophy, prostate cancer, and preventing osteoporosis (brittle bones). It is also used for estrogen replacement therapy after failure of the ovaries and to relieve the symptoms of breast cancer.
When it is not to be taken (Contraindications):
Contraindicated in patients with hypersensitivity; undiagnosed vaginal bleeding; clot in blood vessels; breast cancer, estrogen-dependent tumor; disorders of certain enzymes; pregnancy.
Pregnancy Category :
Category X :Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Dosage & When it is to be taken :
Estradiol dosage varies according to indication and route of administration.
How it should be taken :
It may be administered orally, as an intramuscular injection or applied to the skin or mucous membranes.
Warnings and Precautions :Conditions that become more severe with estrogen include fluid retention; increase in calcium level, poor blood flow to the brain, coronary artery disease, gall bladder diseases; lipid effects; familial defects of lipoprotein metabolism.
May increase blood pressure, risk of blood clot in the vein, breast cancer, benign tumor of the liver, endometrial cancer, dementia and size of preexisting uterine fibroid.
Dosage should be reduced in liver problem and during breastfeeding.
It should not be used in children.
Side Effects :
Central Nervous System- Headache, dizziness, sleeplessness, depression, anxiety, nervousness, migraine.
Gastrointestinal- Abdominal distension, abdominal pain, flatulence, nausea, constipation, upset stomach , diarrhea, bleeding, toothache, tooth disorder.
Skin- Rash, itching, inflammation of the skin, skin scar.
Heart- Temporary loss of consciousness and posture, vein inflammation.
Genitourinary- Abnormal bleeding during menstrual cycles, breast pain, breast tenderness, vaginal bleeding, vaginal discomfort, blood in urine, urinary incontinence.