Ergometrine - Drug InformationGeneric Name : Ergometrine
International :Ergometrina, Ergometrine, Ergotrate, Ergometrin Lek, Ergometrin, Ergometrina maleato Salf, Ergometrina maleato, Ergometrine Injection DBL, Ergometrine Maleate Fresenius, Ergometrine, Ergonovina Drawer, Ergonovina Larjan, Ergonovine Maleate, Ergotrate, Ermetrine, Evina, Maleat de Ergometrinã, Malergo, Metrergina, Metrina, Mitrotan, Sergotonine , Syntometrine
Why it is prescribed (Indications) :
This medication is an ergot alkaloid, prescribed for post-partum and uterine bleeding. It helps the uterus contract back and prevents bleeding after childbirth.
When it is not to be taken (Contraindications):
Contraindicated in patients with vascular disease, psychosis, 1st and 2nd stage of labor, high blood pressure, during pregnancy and spontaneous abortion.
Pregnancy Category :
Category X :Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Dosage & When it is to be taken :
Adult: Oral- 0.2-0.4 mg 2-4 times/day. Max duration: 1 week postpartum.
IV- Excessive uterine bleeding- 200 mcg over at least 1 min, followed by oral doses of 200-400 mcg 2-4 times/day.
How it should be taken :
It comes as a tablet and capsule to take by mouth. It also comes as a solution for injection to be administered by a healthcare provider into the vein.
Warnings and Precautions :Caution should be exercised in patients with history of breech and abnormal fetal presentation, high blood pressure, chronic anemia, heart, liver, kidney, respiratory impairment, breastfeeding and decreased calcium in blood.
Monitor blood pressure, pulse and uterine response while taking this medication.
Side Effects :
Gastrointestinal- Nausea, vomiting, abdominal pain and diarrhea.
Central Nervous System- Headache and dizziness.
Heart- Chest pain, palpitation, high blood pressure, shock and abnormal heart rhythm.
ENT- Ringing in the ear.