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Ephedrine

Latest prescription information about Ephedrine. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Ephedrine
Pronunciation : e-FED-rin
Therapeutic Classification : Decongestants
ICD Code : Y55.5
Trade Name(s): 
India- Efipres Amp, Sulfidrin Inj.
International- Pretz-D.
Why it is prescribed (Indications) : 
This medication is a central nervous system stimulant, prescribed for breathing problems (as a bronchodilator) and for nasal congestion. It is also used for lowering blood pressure. The medication reduces swelling of blood vessels in the nasal passage and widens the air way thereby enhances easy breathing.  
When it is not to be taken (Contraindications): 
Contraindicated in people with adrenal gland tumor, abnormal fast heart rate, hypersensitivity and during breastfeeding.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Dosage & When it is to be taken : 
Adult: PO- Diabetic neuropathic edema- 30-60 mg 3 times/day.
IV- Reversal of spinal or epidural anesthesia-induced hypotension- As 3 mg/ml solution: 3-6 mg, up to 9 mg, may repeat every 3-4 minutes if needed.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider, with or without food.
Warnings and Precautions : 
* Caution should be exercised in patients with history of heart disease, overactive thyroid, diabetes, high blood pressure, increased eye pressure, kidney impairment, prostate enlargement, elderly, during pregnancy.
* It may cause dizziness, drowsiness, do not drive a car or operate machinery while taking this medication.
* If condition worsens, consult with your healthcare provider.
Side Effects : 
Most Common- Nervousness, sleeplessness, fainting, headache, fast heart rate, palpitations and sweating.
Gastrointestinal- Nausea, vomiting and loss of appetite.
Miscellaneous- Muscle spasm, difficulty and painful urination.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it at controlled room temperature (15-25°C).

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Reference  

  • Food and Drug Administration (FDA)
  • National Institutes of Health (NIH)
  • PubMed
  • CIMS
  • Indian Pharma Reference Guide 2012
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