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Generic Name : Entacapone
Pronunciation : en-TAK-a-pone
Therapeutic Classification : Antiparkinson Agents
ICD Code : Y46.7
Trade Name(s): India- Adcapone Tab, Entacom Tab, Syncapone Tab - Carbidopa + Entacapone + Levo-Dopa . International- Comtan. Why it is prescribed (Indications) : This medication is catechol-o-methyltransferase (COMT) inhibitor, used as an adjunct to levodopa/carbidopa to treat patients with idiopathic Parkinson‘s disease. It is used during the later stages when the patient does not respond well to levodopa/carbidopa. It increases the levels of levodopa/carbidopa in the brain, enhancing its effectiveness. When it is not to be taken (Contraindications): Hypersensitivity.
Dosage & When it is to be taken : PO: The recommended dose is 200 mg with each levodopa/carbidopa up to a maximum of 1600 mg/day. How it should be taken : It comes as a tablet to take by mouth. Warnings and Precautions : *It may cause dizziness, lightheadedness, or fainting; do not drive a car or operate machinery, while taking this medication. *Avoid alcohol consumption. *It may lead to an increase in involuntary movements. Caution needed during pregnancy and breastfeeding. Side Effects : Most Common- Diarrhea, movement disorder, nausea, abdominal pain. Skin - Sweating increased Central Nervous System - Involuntary movements, increased or decreased movements, dizziness, anxiety, drowsiness, agitation, and worsening of condition. ENT- Taste perversion Gastrointestinal - Nausea, diarrhea, abdominal pain, constipation, vomiting, dry mouth, indigestion, flatulence, gastritis. Respiratory- Difficulty in breathing. Blood- Easy bruising Genitourinary- Urine discoloration Body as a whole- Back pain, fatigue, weakness Miscellaneous- Bacterial infection. *Stop this medication if unwanted symptoms developed. Storage Conditions : Store it at room temperature and in airtight container. Keep away from children |
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