Information about Entacapone

Generic Name : Entacapone
Up-to-date prescription details regarding Entacapone are provided here.

Pronunciation : en-TAK-a-pone

Learn the correct pronunciation of the Entacapone, understand it's uses, recommended dosages, its indications, how to take, when to take, when not to take, side effects, special precautions, warnings and its and its storage instructions.

You will also find a list of the medication's International and Indian brand or trade names, as well as its pricing information. For verification of the information presented on this page or for additional clarifications, it's advisable to consult your doctor.

ICD Code : Y46.7 Therapeutic Classification : Antiparkinson Agents

Trade Names/Brand Names of Entacapone

India :

Adcapon

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International :

Comtan

Why is Entacapone Prescribed? (Indications)

This medication is catechol-o-methyltransferase (COMT) inhibitor, used as an adjunct to levodopa/carbidopa to treat patients with idiopathic Parkinson‘s disease. It is used during the later stages when the patient does not respond well to levodopa/carbidopa. It increases the levels of levodopa/carbidopa in the brain, enhancing its effectiveness.

When should Entacapone not be taken? (Contraindications)

Hypersensitivity.

What is the dosage of Entacapone?

PO: The recommended dose is 200 mg with each levodopa/carbidopa up to a maximum of 1600 mg/day.

How should Entacapone be taken?

It comes as a tablet to take by mouth.

What are the warnings and precautions for Entacapone?

• It may cause dizziness, lightheadedness, or fainting; do not drive a car or operate machinery, while taking this medication.
• Avoid alcohol consumption.
• It may lead to an increase in involuntary movements.
• Caution needed during pregnancy and breastfeeding.

What are the side effects of Entacapone?

• Most Common- Diarrhea, movement disorder, nausea, abdominal pain.
• Skin - Sweating increased
• Central Nervous System - Involuntary movements, increased or decreased movements, dizziness, anxiety, drowsiness, agitation, and worsening of condition.
• ENT- Taste perversion
• Gastrointestinal - Nausea, diarrhea, abdominal pain, constipation, vomiting, dry mouth, indigestion, flatulence, gastritis.
• Respiratory- Difficulty in breathing.
• Blood- Easy bruising
• Genitourinary- Urine discoloration
• Body as a whole- Back pain, fatigue, weakness
• Miscellaneous- Bacterial infection.