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Generic Name : Efavirenz
Pronunciation : Eff-aa-vy-renz
Trade Name(s):
India- Efavir,Effervin,Estiva,Evirenz,Virang, Viranz, Revenz, Odivir-Kit. International- Sustiva. This medication is a non-nucleoside reverse transcriptase inhibitor (NNRTI), and active antiretroviral therapy (HAART) prescribed for the treatment of human immunodeficiency virus (HIV) type 1 either alone or with other medications. When it is not to be taken (Contraindications):
When it is to be taken : Adult- PO- The recommended dose is 600 mg, once daily. How it should be taken : It comes as a tablet and capsule to take by mouth, on an empty stomach. Special Instruction : * Caution should be exercised in patients with history of high cholesterol, kidney problem, liver problems, seizures, mental illness, any allergy, who are taking other medications, during pregnancy and breastfeeding. * It may cause drowsiness, dizziness, or trouble in concentrating, do not drive a car or operate machinery while taking this medication. * Avoid alcohol consumption. * Since it does not stop the spread of HIV to others, avoid sexual contact, sharing of needles and injection supplies. * Extreme caution needed in children less than 3 years old. * Monitor liver function and cholesterol level while taking this medication. Side Effects : Most Common - Dizziness, nausea, headache, fatigue, sleeplessness and vomiting. Body as a Whole - Allergic reactions, weakness and redistribution/accumulation of body fat. Central Nervous System - Poor concentration, drowsiness, abnormal dreaming, emotion, confusion, agitation, memory loss, hallucinations, stupor, abnormal thinking and depersonalization. Genitourinary - Breast enlargement in male. Gastrointestinal - Constipation and malabsorption. Heart - Flushing and palpitations. Liver - Increase in liver enzyme and liver failure/inflammation. Metabolic - Increased level of cholesterol in blood. Musculoskeletal - Muscle pain and joint pain. Respiratory - Difficulty in breathing. Skin - Redness of the skin and Stevens-Johnson syndrome. Eye and ENT - Abnormal vision and ringing in the ear. * Avoid excess dosage. Storage Conditions : Store it at controlled room temperature (15- 25° C). |
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