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Efalizumab

Latest prescription information about Efalizumab. Learn how to pronounce the drug’s name, its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name(s) of the drug and its price list.
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Generic Name : Efalizumab
Pronunciation : EF-a-LIZ-oo-mab
Trade Name(s): 
International- Raptiva.
Overview : Note: This brand is no longer available in the US market.
Why it is prescribed (Indications) : 
This medication is a recombinant monoclonal antibody, prescribed for chronic, moderate to severe plaque psoriasis.

When it is not to be taken (Contraindications): 


Contraindicated in patients with cancer, decrease in platelet counts, multifocal leukoencephalopathy (PML), and hypersensitivity.

Pregnancy Category :

A B C D X
Category C : Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.


When it is to be taken : 
SC- The recommended dose is 0.7 mg/kg as a single dose followed by weekly doses of 1 mg/kg. Maximum: 200mg.
How it should be taken : 
It comes as a solution for injection to be administered by a healthcare provider under the skin.
Special Instruction : 
* Caution should be exercised in patients with history of cancer, at risk of developing cancer, arthritis, anemia, nerve problems, poor immunity, psoriasis, infections, herpes, syphilis, tuberculosis (TB), any allergy, who are taking other medications, elderly, during pregnancy and breastfeeding.
* It may reduce platelet counts; avoid injury or bruising.
* It should not be used in children.
* Avoid live vaccination during the treatment period.
Side Effects : 
Most Common - Headache, chills, fever, nausea, infections, and muscle pain.
Hypersensitivity - Difficulty in breathing, asthma, hives, life-threatening allergic reactions with or without shock and rash.
Other Precautions : 
* Avoid excess dosage.
Storage Conditions : 
Store it in refrigerator (2-8°C). Do not freeze it.

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